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Academic Journal

Cyclopamine modulates smoothened receptor activity in a binding position dependent manner.

Subjects: *MACHINE learning; *TRANSMEMBRANE domains; *ACTIVATION energy

  • Source: Communications Biology. 9/28/2024, Vol. 7 Issue 1, p1-14. 14p.

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Smoothened receptor inhibitor vismodegib for the treatment of basal cell carcinoma: a retrospective analysis of efficacy and side effects.

Subjects: *BASAL cell carcinoma; *BASAL cell nevus syndrome; *DRUG side effects

  • Source: Journal of Dermatological Treatment. Jun2020, Vol. 31 Issue 4, p387-398. 12p.

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Exploring the Potential of Anthraquinone‐Based Hybrids for Identifying a Novel Generation of Antagonists for the Smoothened Receptor in HH‐Dependent Tumour.

Subjects: *PIPERAZINE; *NATURAL products; *BIOLOGICAL systems

  • Source: Chemistry - A European Journal. 11/8/2023, Vol. 29 Issue 62, p1-9. 9p.

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Structure‐Activity Relationship Studies of Hydantoin‐Cored Ligands for Smoothened Receptor.

Subjects: *STRUCTURE-activity relationships; *BINDING sites; *CRYSTALLIZATION

  • Source: ChemistryOpen. Oct2021, Vol. 10 Issue 10, p1028-1032. 5p.

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Development of a Concise, Asymmetric Synthesis ofa Smoothened Receptor (SMO) Inhibitor: Enzymatic Transamination ofa 4-Piperidinone with Dynamic Kinetic Resolution.

Subjects: *ASYMMETRY (Chemistry); *CHEMICAL inhibitors; *ENZYMATIC analysis

  • Source: Organic Letters. Feb2014, Vol. 16 Issue 3, p860-863. 4p.

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Structural optimization on a virtual screening hit of smoothened receptor.

Subjects: *STRUCTURAL optimization; *BASAL cell carcinoma; *CELL aggregation

  • Source: European Journal of Medicinal Chemistry. Jun2019, Vol. 172, p1-15. 15p.

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Academic Journal

Structure of the human smoothened receptor bound to an antitumour agent.

Subjects: *ANTINEOPLASTIC agents; *CELLULAR signal transduction; *EMBRYOLOGY

  • Source: Nature. 5/16/2013, Vol. 497 Issue 7449, p338-343. 6p. 6 Diagrams.

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Smoothened receptor signaling regulates the developmental shift of GABA polarity in rat somatosensory cortex.

Subjects: *GABA; *CENTRAL nervous system; *HOMEOSTASIS

  • Source: Journal of Cell Science. 2020, Vol. 133 Issue 20, p1-18. 18p.

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Academic Journal

Effect of mutations on drug resistance of smoothened receptor toward inhibitors probed by molecular modeling.

Subjects: *MOLECULAR probes; *DRUG resistance; *MOLECULAR modelsUNITED States. Food & Drug Administration

  • Source: Chemical Physics Letters. Feb2020, Vol. 741, pN.PAG-N.PAG. 1p.

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Computer-aided design of arylphthalazines as potential smoothened receptor antagonists.

Subjects: *COMPUTER-aided design; *GENE expression; *CELLULAR signal transduction

  • Source: Doklady Chemistry. Apr2012, Vol. 443 Issue 2, p97-100. 4p.

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  • 1-10 of  183 results for ""Smoothened Receptor""