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Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study
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- Author(s): Evans, R A; Leavy, O C; Richardson, M; Elneima, O; McAuley, H J C; Shikotra, A; Singapuri, A; Sereno, M; Saunders, R M; Harris, V C; Houchen-Wolloff, L; Aul, R; Beirne, P; Bolton, C E; Brown, J S; Choudhury, G; Diar-Bakerly, N; Easom, N; Echevarria, C; Fuld, J; Hart, N; Hurst, J; Jones, M G; Parekh, D; Pfeffer, P; Rahman, N M; Rowland-Jones, S L; Shah, A M; Wootton, D G; Chalder, T; Davies, M J; De Soyza, A; Geddes, J R; Greenhalf, W; Greening, N J; Heaney, L G; Heller, S; Howard, L S; Jacob, J; Jenkins, R G; Lord, J M; Man, W D-C; McCann, G P; Neubauer, S; Openshaw, P J M; Porter, J C; Rowland, M J; Scott, J T; Semple, M G; Singh, S J; Thomas, D C; Toshner, M; Lewis, K E; Thwaites, R S; Briggs, A; Docherty, A B; Kerr, S; Lone, N I; Quint, J; Sheikh, A; Thorpe, M; Zheng, B; Chalmers, J D; Ho, L P; Horsley, A; Marks, M; Poinasamy, K; Raman, B; Harrison, E M; Wain, L V; Brightling, C E; Abel, K; Adamali, H; Adeloye, D; Adeyemi, O; Adrego, R; Aguilar Jimenez, L A; Ahmad, S; Ahmad Haider, N; Ahmed, R; Ahwireng, N; Ainsworth, M; Al-Sheklly, B; Alamoudi, A; Ali, M; Aljaroof, M; All, AM; Allan, L; Allen, R J; Allerton, L; Allsop, L; Almeida, P; Altmann, D; Alvarez Corral, M; Amoils, S; Anderson, D; Antoniades, C; Arbane, G; Arias, A; Armour, C; Armstrong, L; Armstrong, N; Arnold, D; Arnold, H; Ashish, A; Ashworth, A; Ashworth, M; Aslani, S; Assefa-Kebede, H; Atkin, C; Atkin, P; Aung, H; Austin, L; Avram, C; Ayoub, A; Babores, M; Baggott, R; Bagshaw, J; Baguley, D; Bailey, L; Baillie, J K; Bain, S; Bakali, M; Bakau, M; Baldry, E; Baldwin, D; Ballard, C; Banerjee, A; Bang, B; Barker, R E; Barman, L; Barratt, S; Barrett, F; Basire, D; Basu, N; Bates, M; Bates, A; Batterham, R; Baxendale, H; Bayes, H; Beadsworth, M; Beckett, P; Beggs, M; Begum, M; Bell, D; Bell, R; Bennett, K; Beranova, E; Bermperi, A; Berridge, A; Berry, C; Betts, S; Bevan, E; Bhui, K; Bingham, M; Birchall, K; Bishop, L; Bisnauthsing, K; Blaikely, J; Bloss, A; Bolger, A; Bonnington, J; Botkai, A; Bourne, C; Bourne, M; Bramham, K; Brear, L; Breen, G; Breeze, J; Bright, E; Brill, S; Brindle, K; Broad, L; Broadley, A; Brookes, C; Broome, M; Brown, A; Brown, A; Brown, J; Brown, J; Brown, M; Brown, M; Brown, V; Brugha, T; Brunskill, N; Buch, M; Buckley, P; Bularga, A; Bullmore, E; Burden, L; Burdett, T; Burn, D; Burns, G; Burns, A; Busby, J; Butcher, R; Butt, A; Byrne, S; Cairns, P; Calder, P C; Calvelo, E; Carborn, H; Card, B; Carr, C; Carr, L; Carson, G; Carter, P; Casey, A; Cassar, M; Cavanagh, J; Chablani, M; Chambers, R C; Chan, F; Channon, K M; Chapman, K; Charalambou, A; Chaudhuri, N; Checkley, A; Chen, J; Cheng, Y; Chetham, L; Childs, C; Chilvers, E R; Chinoy, H; Chiribiri, A; Chong-James, K; Choudhury, N; Chowienczyk, P; Christie, C; Chrystal, M; Clark, D; Clark, C; Clarke, J; Clohisey, S; Coakley, G; Coburn, Z; Coetzee, S; Cole, J; Coleman, C; Conneh, F; Connell, D; Connolly, B; Connor, L; Cook, A; Cooper, B; Cooper, J; Cooper, S; Copeland, D; Cosier, T; Coulding, M; Coupland, C; Cox, E; Craig, T; Crisp, P; Cristiano, D; Crooks, M G; Cross, A; Cruz, I; Cullinan, P; Cuthbertson, D; Daines, L; Dalton, M; Daly, P; Daniels, A; Dark, P; Dasgin, J; David, A; David, C; Davies, E; Davies, F; Davies, G; Davies, G A; Davies, K; Dawson, J; Daynes, E; Deakin, B; Deans, A; Deas, C; Deery, J; Defres, S; Dell, A; Dempsey, K; Denneny, E; Dennis, J; Dewar, A; Dharmagunawardena, R; Dickens, C; Dipper, A; Diver, S; Diwanji, S N; Dixon, M; Djukanovic, R; Dobson, H; Dobson, S L; Donaldson, A; Dong, T; Dormand, N; Dougherty, A; Dowling, R; Drain, S; Draxlbauer, K; Drury, K; Dulawan, P; Dunleavy, A; Dunn, S; Earley, J; Edwards, S; Edwardson, C; El-Taweel, H; Elliott, A; Elliott, K; Ellis, Y; Elmer, A; Evans, D; Evans, H; Evans, J; Evans, R; Evans, R I; Evans, T; Evenden, C; Evison, L; Fabbri, L; Fairbairn, S; Fairman, A; Fallon, K; Faluyi, D; Favager, C; Fayzan, T; Featherstone, J; Felton, T; Finch, J; Finney, S; Finnigan, J; Finnigan, L; Fisher, H; Fletcher, S; Flockton, R; Flynn, M; Foot, H; Foote, D; Ford, A; Forton, D; Fraile, E; Francis, C; Francis, R; Francis, S; Frankel, A; Fraser, E; Free, R; French, N; Fu, X; Furniss, J; Garner, L; Gautam, N; George, J; George, P; Gibbons, M; Gill, M; Gilmour, L; Gleeson, F; Glossop, J; Glover, S; Goodman, N; Goodwin, C; Gooptu, B; Gordon, H; Gorsuch, T; Greatorex, M; Greenhaff, P L; Greenhalgh, A; Greenwood, J; Gregory, H; Gregory, R; Grieve, D; Griffin, D; Griffiths, L; Guerdette, A-M; Guillen Guio, B; Gummadi, M; Gupta, A; Gurram, S; Guthrie, E; Guy, Z; H Henson, H; Hadley, K; Haggar, A; Hainey, K; Hairsine, B; Haldar, P; Hall, I; Hall, L; Halling-Brown, M; Hamil, R; Hancock, A; Hancock, K; Hanley, N A; Haq, S; Hardwick, H E; Hardy, E; Hardy, T; Hargadon, B; Harrington, K; Harris, E; Harrison, P; Harvey, A; Harvey, M; Harvie, M; Haslam, L; Havinden-Williams, M; Hawkes, J; Hawkings, N; Haworth, J; Hayday, A; Haynes, M; Hazeldine, J; Hazelton, T; Heeley, C; Heeney, J L; Heightman, M; Henderson, M; Hesselden, L; Hewitt, M; Highett, V; Hillman, T; Hiwot, T; Hoare, A; Hoare, M; Hockridge, J; Hogarth, P; Holbourn, A; Holden, S; Holdsworth, L; Holgate, D; Holland, M; Holloway, L; Holmes, K; Holmes, M; Holroyd-Hind, B; Holt, L; Hormis, A; Hosseini, A; Hotopf, M; Howard, K; Howell, A; Hufton, E; Hughes, A D; Hughes, J; Hughes, R; Humphries, A; Huneke, N; Hurditch, E; Husain, M; Hussell, T; Hutchinson, J; Ibrahim, W; Ilyas, F; Ingham, J; Ingram, L; Ionita, D; Isaacs, K; Ismail, K; Jackson, T; James, W Y; Jarman, C; Jarrold, I; Jarvis, H; Jastrub, R; Jayaraman, B; Jezzard, P; Jiwa, K; Johnson, C; Johnson, S; Johnston, D; Jolley, C J; Jones, D; Jones, G; Jones, H; Jones, H; Jones, I; Jones, L; Jones, S; Jose, S; Kabir, T; Kaltsakas, G; Kamwa, V; Kanellakis, N; Kaprowska, s; Kausar, Z; Keenan, N; Kelly, S; Kemp, G; Kerslake, H; Key, A L; Khan, F; Khunti, K; Kilroy, S; King, B; King, C; Kingham, L; Kirk, J; Kitterick, P; Klenerman, P; Knibbs, L; Knight, S; Knighton, A; Kon, O; Kon, S; Kon, S S; Koprowska, S; Korszun, A; Koychev, I; Kurasz, C; Kurupati, P; Laing, C; Lamlum, H; Landers, G; Langenberg, C; Lasserson, D; Lavelle-Langham, L; Lawrie, A; Lawson, C; Lawson, C; Layton, A; Lea, A; Lee, D; Lee, J-H; Lee, E; Leitch, K; Lenagh, R; Lewis, D; Lewis, J; Lewis, V; Lewis-Burke, N; Li, X; Light, T; Lightstone, L; Lilaonitkul, W; Lim, L; Linford, S; Lingford-Hughes, A; Lipman, M; Liyanage, K; Lloyd, A; Logan, S; Lomas, D; Loosley, R; Lota, H; Lovegrove, W; Lucey, A; Lukaschuk, E; Lye, A; Lynch, C; MacDonald, S; MacGowan, G; Macharia, I; Mackie, J; Macliver, L; Madathil, S; Madzamba, G; Magee, N; Magtoto, M M; Mairs, N; Majeed, N; Major, E; Malein, F; Malim, M; Mallison, G; Mandal, S; Mangion, K; Manisty, C; Manley, R; March, K; Marciniak, S; Marino, P; Mariveles, M; Marouzet, E; Marsh, S; Marshall, B; Marshall, M; Martin, J; Martineau, A; Martinez, L M; Maskell, N; Matila, D; Matimba-Mupaya, W; Matthews, L; Mbuyisa, A; McAdoo, S; Weir McCall, J; McAllister-Williams, H; McArdle, A; McArdle, P; McAulay, D; McCormick, J; McCormick, W; 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Orriss-Dib, L; Osborne, L; Osbourne, R; Ostermann, M; Overton, C; Owen, J; Oxton, J; Pack, J; Pacpaco, E; Paddick, S; Painter, S; Pakzad, A; Palmer, S; Papineni, P; Paques, K; Paradowski, K; Pareek, M; Parfrey, H; Pariante, C; Parker, S; Parkes, M; Parmar, J; Patale, S; Patel, B; Patel, M; Patel, S; Pattenadk, D; Pavlides, M; Payne, S; Pearce, L; Pearl, J E; Peckham, D; Pendlebury, J; Peng, Y; Pennington, C; Peralta, I; Perkins, E; Peterkin, Z; Peto, T; Petousi, N; Petrie, J; Phipps, J; Pimm, J; Piper Hanley, K; Pius, R; Plant, H; Plein, S; Plekhanova, T; Plowright, M; Polgar, O; Poll, L; Porter, J; Portukhay, S; Powell, N; Prabhu, A; Pratt, J; Price, A; Price, C; Price, C; Price, D; Price, L; Price, L; Prickett, A; Propescu, J; Pugmire, S; Quaid, S; Quigley, J; Qureshi, H; Qureshi, I N; Radhakrishnan, K; Ralser, M; Ramos, A; Ramos, H; Rangeley, J; Rangelov, B; Ratcliffe, L; Ravencroft, P; Reddington, A; Reddy, R; Redfearn, H; Redwood, D; Reed, A; Rees, M; Rees, T; Regan, K; Reynolds, W; Ribeiro, C; Richards, A; Richardson, E; Rivera-Ortega, P; Roberts, K; Robertson, E; Robinson, E; Robinson, L; Roche, L; Roddis, C; Rodger, J; Ross, A; Ross, G; Rossdale, J; Rostron, A; Rowe, A; Rowland, A; Rowland, J; Roy, K; Roy, M; Rudan, I; Russell, R; Russell, E; Saalmink, G; Sabit, R; Sage, E K; Samakomva, T; Samani, N; Sampson, C; Samuel, K; Samuel, R; Sanderson, A; Sapey, E; Saralaya, D; Sargant, J; Sarginson, C; Sass, T; Sattar, N; Saunders, K; Saunders, P; Saunders, L C; Savill, H; Saxon, W; Sayer, A; Schronce, J; Schwaeble, W; Scott, K; Selby, N; Sewell, T A; Shah, K; Shah, P; Shankar-Hari, M; Sharma, M; Sharpe, C; Sharpe, M; Shashaa, S; Shaw, A; Shaw, K; Shaw, V; Shelton, S; Shenton, L; Shevket, K; Short, J; Siddique, S; Siddiqui, S; Sidebottom, J; Sigfrid, L; Simons, G; Simpson, J; Simpson, N; Singh, C; Singh, S; Sissons, D; Skeemer, J; Slack, K; Smith, A; Smith, D; Smith, S; Smith, J; Smith, L; Soares, M; Solano, T S; Solly, R; Solstice, AR; Soulsby, T; Southern, D; Sowter, D; 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Wajero, L O; Walder, S; Walker, S; Walker, S; Wall, E; Wallis, T; Walmsley, S; Walsh, J A; Walsh, S; Warburton, L; Ward, T J C; Warwick, K; Wassall, H; Waterson, S; Watson, E; Watson, L; Watson, J; Welch, C; Welch, H; Welsh, B; Wessely, S; West, S; Weston, H; Wheeler, H; White, S; Whitehead, V; Whitney, J; Whittaker, S; Whittam, B; Whitworth, V; Wight, A; Wild, J; Wilkins, M; Wilkinson, D; Williams, N; Williams, N; Williams, J; Williams-Howard, S A; Willicombe, M; Willis, G; Willoughby, J; Wilson, A; Wilson, D; Wilson, I; Window, N; Witham, M; Wolf-Roberts, R; Wood, C; Woodhead, F; Woods, J; Wormleighton, J; Worsley, J; Wraith, D; Wrey Brown, C; Wright, C; Wright, L; Wright, S; Wyles, J; Wynter, I; Xu, M; Yasmin, N; Yasmin, S; Yates, T; Yip, K P; Young, B; Young, S; Young, A; Yousuf, A J; Zawia, A; Zeidan, L; Zhao, B; Zongo, O
- Source:
The Lancet Respiratory Medicine; August 2022, Vol. 10 Issue: 8 p761-775, 15p - Source:
- Additional Information
- Abstract: No effective pharmacological or non-pharmacological interventions exist for patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for COVID-19, identify factors associated with patient-perceived recovery, and identify potential therapeutic targets by describing the underlying inflammatory profiles of the previously described recovery clusters at 5 months after hospital discharge.
- Abstract:
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