Antibiotic Resistance in Urinary Tract Infections in College Students

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  • Author(s): Olson, Ronald P.; Haith, Karen
  • Language:
    English
  • Source:
    Journal of American College Health. 2012 60(6):471-474.
  • Physical Description:
    PDF
  • Publication Date:
    2012
  • Document Type:
    Journal Articles
    Reports - Research
  • Additional Information
    • Availability:
      Routledge. Available from: Taylor & Francis, Ltd. 325 Chestnut Street Suite 800, Philadelphia, PA 19106. Tel: 800-354-1420; Fax: 215-625-2940; Web site: http://www.tandf.co.uk/journals
    • Peer Reviewed:
      Y
    • Source:
      4
    • Education Level:
      Higher Education
    • Subject Terms:
      Sexuality; Females; Public Health; Microbiology; Drug Therapy; College Students; Patients; Symptoms (Individual Disorders); Diagnostic Tests; Prediction
    • Accession Number:
      10.1080/07448481.2012.681410
    • ISSN:
      0744-8481
    • Abstract:
      Objective: To determine resistance to antibiotics of "Escherichia coli" in uncomplicated urinary tract infections (uUTIs) in female college students. Participants: Symptomatic patients presenting to a student health service from September 2008 to December 2009. Methods: Clean catch midstream urine samples were tested for urinalysis (UA) and culture and sensitivity. Results: Of 168 students enrolled in the study, 138 had positive UA, and 94 of these grew greater than 100,000 colonies/mL of "E. coli". Ampicillin resistance was 31.9%, trimethoprim-sulfamethoxazole (TMP-SMX) resistance 16.0%, ciprofloxacin resistance 4.3%, amoxicillin/clavulanate resistance 3.2%, and nitrofurantoin resistance 1.1%. The sensitivity of UA was 95.4% and the positive predictive value was 87.0% (p [less than or equal to] 0.001). Specificity was 77.5% and negative predictive value 92.9%. Conclusions: In healthy college women with uUTI symptoms, TMP-SMX should not be universally used for empirical therapy, whereas use of ciprofloxacin, amoxicillin/clavulanate, and nitrofurantoin are appropriate.
    • Abstract:
      As Provided
    • Number of References:
      40
    • Publication Date:
      2013
    • Accession Number:
      EJ994451