Thinking Inside the Box: Endogenous α-Anomeric Lipid Antigens.

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    • Abstract:
      The most powerful iNKT cell antigen is α-galactosylceramide (α-GalCer), derived from the marine sponge. However, α-anomeric glycolipids are thought to be absent in mammals. In this issue of Immunity , Kain et al., (2014) demonstrate the presence of mammalian α-linked glycosylceramides, such as α-GalCer. [ABSTRACT FROM AUTHOR]
    • Abstract:
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