[Endothelial cells and leukocytes--significance of adhesion interactions].

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  • Author(s): Krejsek J;Krejsek J; Kopecký O
  • Source:
    Vnitrni lekarstvi [Vnitr Lek] 1998 Jan; Vol. 44 (1), pp. 42-5.
  • Publication Type:
    English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • Language:
    Czech
  • Additional Information
    • Transliterated Title:
      Endoteliální bunky a leukocyty--význam adhezních interakcí.
    • Source:
      Publisher: Ambit Media Country of Publication: Czech Republic NLM ID: 0413602 Publication Model: Print Cited Medium: Print ISSN: 0042-773X (Print) Linking ISSN: 0042773X NLM ISO Abbreviation: Vnitr Lek Subsets: MEDLINE
    • Publication Information:
      Publication: 2010- : Brno : Ambit Media
      Original Publication: 1973-<1994> : Praha : Avicenum
    • Subject Terms:
      Endothelium, Vascular/*physiology ; Leukocytes/*physiology; Cell Adhesion ; Cell Adhesion Molecules/physiology ; Cell Communication ; Endothelium, Vascular/cytology
    • Abstract:
      Interactions between endothelial cells, adherence of endothelial cells to the molecules of extracellular matrix, adhesion of leukocytes and platelets to the activated endothelial cell lining are mediated by adhesion molecules belonging into four families: immunoglobulins, integrins, selectins, and cadherins. Adhesion interactions mediate intercellular signaling. Soluble forms of adhesion molecules modulate adhesion interactions. The determination of soluble adhesion molecules in blood is used for indirect evaluation of function or dysfunction of endothelial cells. It is possible to modulate abnormal function of endothelial cells using monoclonal antibodies against adhesion molecules.
    • Accession Number:
      0 (Cell Adhesion Molecules)
    • Publication Date:
      Date Created: 19980929 Date Completed: 19981020 Latest Revision: 20061115
    • Publication Date:
      20221213
    • Accession Number:
      9750483