Presents details of a report on renal-stone disease. Aims of treatment; The benefits of a better understanding of abnormalities of renal-tubular transport mechanisms; Details of three patients with renal-stone disease; The mechanisms of urinary acidification; Defective proton secretion and distal renal tubular acidosis (dRTA); The effect of erythrocytes; The features of nephrolithiasis; A positional cloning approach to hereditary nepholithiasis.
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