Pretibial myxedema with Graves' disease: a case report and review of Japanese literature.

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  • Author(s): Ishizawa T;Ishizawa T; Sugiki H; Anzai S; Kondo S
  • Source:
    The Journal of dermatology [J Dermatol] 1998 Apr; Vol. 25 (4), pp. 264-8.
  • Publication Type:
    Case Reports; Journal Article; Review
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7600545 Publication Model: Print Cited Medium: Print ISSN: 0385-2407 (Print) Linking ISSN: 03852407 NLM ISO Abbreviation: J Dermatol Subsets: MEDLINE
    • Publication Information:
      Publication: London : Wiley-Blackwell
      Original Publication: Tokyo, Japanese Dermatological Association, <-2005>
    • Subject Terms:
      Graves Disease/*complications ; Leg Dermatoses/*complications ; Myxedema/*complications; Adolescent ; Antithyroid Agents/therapeutic use ; Biopsy, Needle ; Female ; Graves Disease/diagnosis ; Graves Disease/drug therapy ; Humans ; Japan ; Leg Dermatoses/pathology ; Methimazole/therapeutic use ; Myxedema/pathology
    • Abstract:
      We report a case of pretibial myxedema with Graves' disease in an 18-year-old Japanese woman. The physical examination revealed waxy indurated plaques with prominent hair follicle openings and nonpitting edema disseminated on her lower legs. Histology from an edematous lesion revealed that the dermis was markedly thickened with abundant mucin, especially hyaluronic acid, and the collagen fibers in this portion were splitting up into fibrils. We also reviewed 112 cases of pretibial myxedema reported in the Japanese literature.
    • Number of References:
      8
    • Accession Number:
      0 (Antithyroid Agents)
      554Z48XN5E (Methimazole)
    • Publication Date:
      Date Created: 19980604 Date Completed: 19980630 Latest Revision: 20190826
    • Publication Date:
      20231215
    • Accession Number:
      10.1111/j.1346-8138.1998.tb02394.x
    • Accession Number:
      9609987