Carboplatin-induced Fanconi-like syndrome in rats: Amelioration by pentoxifylline.

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    • Abstract:
      Highlights: [•] Carboplatin, like cisplatin, induces ROS-dependent nephrotoxicity. [•] Carboplatin induced renal damage resembles Fanconi-like condition. [•] Carboplatin intoxication causes aminoaciduria-specifically tyrosinuria and cysteineuria. [•] ATPases, GSH and TBARS are affected significantly with carboplatin. [•] Pentoxifylline mitigates carboplatin induced renal insult. [ABSTRACT FROM AUTHOR]
    • Abstract:
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