[Hepatitis GBV isolated in acute liver failure. Successful outcome after liver transplantation].

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Transliterated Title:
      Hepatit GBV isolerades vid akut leversvikt. Lyckligt förlopp tack vare transplantation.
    • Source:
      Publisher: Sveriges Lakarforbund Country of Publication: Sweden NLM ID: 0027707 Publication Model: Print Cited Medium: Print ISSN: 0023-7205 (Print) Linking ISSN: 00237205 NLM ISO Abbreviation: Lakartidningen Subsets: MEDLINE
    • Publication Information:
      Original Publication: Stockholm : Sveriges Lakarforbund
    • Subject Terms:
      Liver Transplantation*; Flaviviridae/*isolation & purification ; Hepatic Encephalopathy/*virology; Adolescent ; Female ; Hepatic Encephalopathy/diagnosis ; Hepatic Encephalopathy/surgery ; Humans ; Prognosis
    • Abstract:
      Fulminant hepatic failure is a life-threatening condition associated with a mortality of approximately 80 per cent. Liver transplantation may be the only life-saving recourse in such cases. The condition can be caused by any of a number of different agencies such as viral infection, or toxic, circulatory or metabolic factors, though in a large proportion of cases the aetiology is unknown. Recently, knowledge has accumulated of a new hepatitis virus, hepatitis GB virus (HGBV), a Flavivirus remotely related to hepatitis C. The clinical significance of this virus is unclear. It is found in 3-4 per cent of blood donors, and most HGBV-positive patients are asymptomatic though some develop fulminant hepatic failure. The article consists in a case report of fulminant hepatic failure in a 17-year-old woman where no possible aetiological factor could be identified, other than her HGBV-positivity. The patient underwent a successful liver transplantation and is now, 18 months later, in excellent condition. She is still HGBV-positive but manifests no hepatic effects. Whether HGBV infection was responsible for the hepatic failure remains unclear, however.
    • Publication Date:
      Date Created: 19971231 Date Completed: 19971204 Latest Revision: 20061115
    • Publication Date:
      20231215
    • Accession Number:
      9411092