The Cosmetics Europe strategy for animal-free genotoxicity testing: Project status up-date.

Highlights: [•] Overview of the Cosmetics Europe Genotoxicity Task projects. [•] Improved specificity by selecting relevant cells and sensitive toxicity measures. [•] Develop and validate human 3D skin models for micronucleus and Comet assays. [•] Investigated enzyme capacities of human skin and RS models. [•] Initial assay predictivity improved and new models for genotoxic hazard assessment. [Copyright &y& Elsevier]

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