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Antibodies are forever: a study using 12-26-year-old expired antibodies.
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- Author(s): Argentieri, Maria C1; Pilla, Daniela1; Vanzati, Alice1,2; Lonardi, Silvia3; Facchetti, Fabio3; Doglioni, Claudio4; Parravicini, Carlo5; Cattoretti, Giorgio1,2
- Source:
Histopathology. Dec2013, Vol. 63 Issue 6, p869-876. 8p.
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- Additional Information
- Abstract:
Aims The aim of this study was to investigate whether the shelf-life of diagnostic antibodies is longer than the expiry date on the label. Methods and results Four independent laboratories tested a small number of diagnostic antibodies kept at +4°C for 12-26 years, and found them to work perfectly on routine histology sections. Conclusions Diagnostic antibodies may have a workable half-life in excess of 10 years, and the emphasis on performance should shift to the preservation of antigenic targets in the tissue. [ABSTRACT FROM AUTHOR]
- Abstract:
Copyright of Histopathology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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