Clinical neurologic indices of toxicity in animals.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read Online Read More Add to Saved list
  • Author(s): O'Donoghue JL;O'Donoghue JL
  • Source:
    Environmental health perspectives [Environ Health Perspect] 1996 Apr; Vol. 104 Suppl 2, pp. 323-30.
  • Publication Type:
    Journal Article; Review
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication Model: Print Cited Medium: Print ISSN: 0091-6765 (Print) Linking ISSN: 00916765 NLM ISO Abbreviation: Environ Health Perspect Subsets: MEDLINE
    • Publication Information:
      Original Publication: Research Triangle Park, N. C. National Institute of Environmental Health Sciences.
    • Subject Terms:
      Nervous System Diseases/*chemically induced ; Neurotoxins/*toxicity; Animals ; Arousal/drug effects ; Brain Mapping ; Cranial Nerves/drug effects ; Neurologic Examination ; Seizures/etiology ; Toxicity Tests/methods
    • Abstract:
      The fundamental structures and functions of the nervous systems of animals and humans are conserved in many ways across species. These similarities provide a basis for developing common neurologic examinations for a number of species of animals and also provide a basis for developing risk assessments across species for neurologic end points. The neurologic examination requires no expensive equipment and can be conducted in the field or wherever impaired animals are identified. The proper conduct of neurologic examinations in animals assumes that the examiner has a fundamental understanding of the normal structure and function of the nervous system as well as knowledge about the spontaneous disease background of the species being studied.
    • Number of References:
      13
    • References:
      Exp Neurol. 1969 Nov;25(3):295-330. (PMID: 4981856)
      J Toxicol Environ Health. 1982 May-Jun;9(5-6):691-704. (PMID: 6750143)
      Am J Vet Res. 1974 Jul;35(7):1005-7. (PMID: 4843043)
      Science. 1971 Oct 29;174(4008):523-5. (PMID: 5165007)
    • Accession Number:
      0 (Neurotoxins)
    • Publication Date:
      Date Created: 19960401 Date Completed: 19970610 Latest Revision: 20181113
    • Publication Date:
      20221213
    • Accession Number:
      PMC1469587
    • Accession Number:
      10.1289/ehp.96104s2323
    • Accession Number:
      9182039