The effects and mechanisms of action of diethylcarbamazine citrate in isolated rat hearts.

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    • Alternate Title:
      Dietilkarbamazin sitrat'ın izole sıçan kalplerindeki etkileri ve etki mekanizmaları.
    • Abstract:
      The article discusses the mechanism of action and effects of the anthelmintic drug diethylcarbamazine citrate (DECC) in isolated rat hearts. It mentions that the drug is used in the treatment of filarial infections. It states the intravenous administration of the drug induces various symptoms including hypotension, bradycardia and reduction in left ventricular pressure. It discusses the biochemical pathways that regulate the actions of DECC such as signal transduction.