[Immunophenotypic characterization of cutaneous neuroendocrine carcinoma derived from Merkel cells].

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  • Additional Information
    • Transliterated Title:
      Immunofenotipicheskaia kharakteristika neĭroéndokrinnogo raka kozhi iz kletok Merkelia.
    • Source:
      Publisher: Media Sfera Country of Publication: Russia (Federation) NLM ID: 0370604 Publication Model: Print Cited Medium: Print ISSN: 0004-1955 (Print) Linking ISSN: 00041955 NLM ISO Abbreviation: Arkh Patol Subsets: MEDLINE
    • Publication Information:
      Publication: Moskva : Media Sfera
      Original Publication: Moskva : Medicina
    • Subject Terms:
      Carcinoma, Merkel Cell/*chemistry ; Skin Neoplasms/*chemistry; Adult ; Aged ; Biomarkers/chemistry ; Carcinoma, Merkel Cell/pathology ; Cell Differentiation/physiology ; Diagnosis, Differential ; Female ; Humans ; Immunohistochemistry ; Immunophenotyping ; Male ; Middle Aged ; Skin Neoplasms/pathology
    • Abstract:
      The following immunohistochemical markers were studied in 5 Merkel cell carcinomas: cytokeratins, epithelial membrane component, neuron-specific enolase, synaptophysin and chromogranin A. High expression of these markers in tumors allows one to consider them as having epithelial origin with neuroendocrine differentiation. Common leucocytic antigen proved to be very useful in differential diagnosis with malignant lymphoma.
    • Accession Number:
      0 (Biomarkers)
    • Publication Date:
      Date Created: 19960901 Date Completed: 19970129 Latest Revision: 20151119
    • Publication Date:
      20221213
    • Accession Number:
      9005817