[Insulin resistance and hyperinsulinemia--clinical aspects].

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  • Author(s): Kozek E;Kozek E
  • Source:
    Przeglad lekarski [Przegl Lek] 1996; Vol. 53 (9), pp. 647-52.
  • Publication Type:
    English Abstract; Journal Article; Review
  • Language:
    Polish
  • Additional Information
    • Transliterated Title:
      Insulinooporność i hiperinsulinemia--aspekty kliniczne.
    • Source:
      Publisher: Wydawnicto Przeglad Lekarski Country of Publication: Poland NLM ID: 19840720R Publication Model: Print Cited Medium: Print ISSN: 0033-2240 (Print) Linking ISSN: 00332240 NLM ISO Abbreviation: Przegl Lek Subsets: MEDLINE
    • Publication Information:
      Original Publication: Kraków : Wydawnicto Przeglad Lekarski
    • Subject Terms:
      Arteriosclerosis/*prevention & control ; Cerebrovascular Disorders/*prevention & control ; Coronary Disease/*prevention & control ; Hyperinsulinism/*therapy; Arteriosclerosis/etiology ; Cerebrovascular Disorders/etiology ; Coronary Disease/etiology ; Humans ; Hyperinsulinism/complications ; Hyperlipidemias/complications ; Hypertension/complications ; Insulin Resistance ; Obesity/complications
    • Abstract:
      A group of metabolic disorders including insulin resistance and hyperinsulinemia, impaired glucose tolerance, visceral obesity, hypertension, dyslipidemia, hyperuricemia, hypercoagulability and microalbuminuria determine the risk for the development of atherosclerosis, coronary artery disease and cerebral vascular disorders. Although available studies on the pathogenesis of the metabolic syndrome are equivocal, it is most frequently hypothesized that hereditary of insulin resistance leads to the remaining metabolic disorders including diabetes mellitus, atherosclerosis and coronary artery disease. Despite pathogenetic controversies, there are convincing arguments for the diagnosis of the metabolic syndrome and search for therapy improving insulin sensitivity and reducing hyperinsulinemia thus preventing the development of diabetes mellitus and coronary artery disease.
    • Number of References:
      51
    • Publication Date:
      Date Created: 19960101 Date Completed: 19970114 Latest Revision: 20061115
    • Publication Date:
      20240829
    • Accession Number:
      8992530