Urinary chloride excretion distinguishes between renal and extrarenal metabolic alkalosis.

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  • Additional Information
    • Source:
      Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Print Cited Medium: Print ISSN: 0340-6199 (Print) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE
    • Publication Information:
      Publication: Berlin : Springer Verlag
      Original Publication: Berlin, New York, Springer-Verlag.
    • Subject Terms:
      Alkalosis/*etiology ; Alkalosis/*urine ; Chlorides/*urine ; Kidney Diseases/*urine; Adolescent ; Bartter Syndrome/urine ; Case-Control Studies ; Child ; Child, Preschool ; Diagnosis, Differential ; Diuretics/urine ; Female ; Humans ; Infant ; Kidney Diseases/complications ; Male ; Potassium/urine ; Reference Values ; Sodium/urine ; Switzerland
    • Abstract:
      Unlabelled: The aetiology of normotensive hypokalaemic metabolic alkalosis is sometimes not obtainable from the history. Observations in adults indicate that the urinary chloride excretion is low in metabolic alkalosis of extrarenal origin. The chloride/creatinine ratio in random urines was therefore compared in 283 healthy children and in eight paediatric patients with metabolic alkalosis. The urinary chloride/creatinine ratio was reduced in four patients with metabolic alkalosis of extrarenal origin and within reference values or above in four patients with metabolic alkalosis of renal origin.
      Conclusion: The study confirms that urinary chloride/creatinine ratio discriminates between extrarenal and renal forms of metabolic alkalosis.
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    • Accession Number:
      0 (Chlorides)
      0 (Diuretics)
      9NEZ333N27 (Sodium)
      RWP5GA015D (Potassium)
    • Publication Date:
      Date Created: 19951201 Date Completed: 19960927 Latest Revision: 20220310
    • Publication Date:
      20250114
    • Accession Number:
      10.1007/BF01958641
    • Accession Number:
      8801106