T cell receptor V-segment frequencies in aged individuals.

Publisher: Informa Healthcare Country of Publication: England NLM ID: 8504629 Publication Model: Print Cited Medium: Print ISSN: 0882-0139 (Print) Linking ISSN: 08820139 NLM ISO Abbreviation: Immunol Invest Subsets: MEDLINE

Publication: London : Informa Healthcare
Original Publication: New York, N.Y. : M. Dekker, c1985-

Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor* ; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor*; Aging/*immunology; Adult ; Aged ; Aged, 80 and over ; Aging/genetics ; Antibodies, Monoclonal/immunology ; Epitopes/analysis ; Female ; Humans ; Male ; Middle Aged ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/immunology ; Spain ; T-Lymphocytes/immunology

The T V alpha and V beta cell specificities repertoire usage in aging subjects was studied by the use of seven different monoclonal antibodies specific for defined regions of the T cell receptor (TCR). Except for the V beta 8 subfamily, no differences were observed in the frequency of T cells bearing selected V alpha beta epitopes, between old and control subjects.

0 (Antibodies, Monoclonal)
0 (Epitopes)
0 (Receptors, Antigen, T-Cell, alpha-beta)

Date Created: 19960101 Date Completed: 19960815 Latest Revision: 20191024

20221213

10.3109/08820139609059295

8675227