[The use of the screening of maternal serum factors for the prenatal diagnosis of fetal developmental defects and chromosomal diseases].

Ispol'zovanie skrininga faktorov materinskoĭ syvorotki dlia prenatal'noĭ diagnostiki porokov razvitiia i khromosomnykh zabolevaniĭ ploda.

Publisher: Izdatelstvo Naukova Dumka Country of Publication: Ukraine NLM ID: 0101671 Publication Model: Print Cited Medium: Print ISSN: 0564-3783 (Print) Linking ISSN: 05643783 NLM ISO Abbreviation: Tsitol Genet Subsets: MEDLINE

Publication: Kiev : Izdatelstvo Naukova Dumka
Original Publication: Kiev.

Chorionic Gonadotropin/*blood ; Congenital Abnormalities/*diagnosis ; Congenital Abnormalities/*prevention & control ; Fetal Diseases/*diagnosis ; Fetal Diseases/*prevention & control ; Mass Screening/*methods ; Prenatal Diagnosis/*methods ; alpha-Fetoproteins/*analysis; Adolescent ; Adult ; Female ; Humans ; Pregnancy ; Pregnancy Trimester, First ; Pregnancy Trimester, Second ; Prenatal Diagnosis/statistics & numerical data ; Ukraine

The association of the levels of alpha-fetoprotein and chorionic gonadotropin with congenital developmental defects and chromosomal abnormalities of fetus was studied. The correlation of elevated level of alpha-fetoprotein with defects of neuraxis, kidney and abdominal wall of fetus was shown. These data are used for screening of women with a high risk for Down's syndrome and other chromosomal abnormalities.

0 (Chorionic Gonadotropin)
0 (alpha-Fetoproteins)

Date Created: 19950701 Date Completed: 19960515 Latest Revision: 20080215

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