The Rotavirus Saga Revisited.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Author(s): Shaw, Alan R.
  • Source:
    Annual Review of Medicine. 2013, Vol. 64 Issue 1, p165-174. 17p.
  • Additional Information
    • Subject Terms:
      ROTAVIRUS vaccines; INTESTINAL intussusception; DRUG administration; PLACEBOS; DEVELOPING countries; DIARRHEA
    • Abstract:
      Two live oral rotavirus vaccines were approved by the US Food and Drug Administration in 2005 and 2008, following large studies of ∼70,000 each in order to address questions about intussusception triggered by a third earlier vaccine. Both new rotavirus vaccines showed almost identical rates of intussusception in vaccine and placebo recipients. These vaccines have been used extensively in the United States with positive results. Efforts are under way to implement these vaccines in developing countries where the need is greatest. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Annual Review of Medicine is the property of Annual Reviews Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)