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The Best Possible Intentions: Testing Prophylactic Approaches on Humans in Developing Countries.
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- Author(s): LöWy, Ilana
- Source:
American Journal of Public Health. Feb2013, Vol. 103 Issue 2, p226-237. 12p. - Source:
- Additional Information
- Subject Terms: PREVENTION of sexually transmitted diseases; VIRUS disease drug therapy; EXPERIMENTAL design; INFORMED consent (Medical law); INTENTION; INTERPROFESSIONAL relations; INVESTMENTS; PRISONERS; MEDICAL ethics; HISTORY of medicine; MOTIVATION (Psychology); POVERTY; SEXUALLY transmitted diseases; COMMUNITY support; YELLOW fever; RESEARCH; HUMAN research subjects; HISTORY; PREVENTION; SAFETY
- Subject Terms:
- Abstract: Debates on human experiments in developing countries focus on ethical principles such as informed consent, accountability, involvement of the concerned communities, and the improvement of local health services. Public health specialists who conducted human experiments in Rio de Janeiro (1902-1905) and in Guatemala (1947-1948) believed, however, that they were acting in the best interests of local populations, were aware of the importance of informed consent, were closely collaborating with local health professionals, and were contributing to the development of local health structures. Nevertheless, their investigations went dramatically wrong. An initial desire to conduct ethically and scientifically sound studies was undermined by pressure to obtain results and to save the researchers' initial investment, the possibility of freely using hospitalized patients as experimental participants, uncritical help from local professional elites, and structural pitfalls of experimenting with severely deprived people. These elements can still be found in trials of preventive methods in the Global South. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of American Journal of Public Health is the property of American Public Health Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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