Improvement of pregnancy rates with oocyte donation in older recipients with the addition of progesterone vaginal suppositories.

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  • Additional Information
    • Source:
      Publisher: Elsevier for the American Society for Reproductive Medicine Country of Publication: United States NLM ID: 0372772 Publication Model: Print Cited Medium: Print ISSN: 0015-0282 (Print) Linking ISSN: 00150282 NLM ISO Abbreviation: Fertil Steril Subsets: MEDLINE
    • Publication Information:
      Publication: New York. NY : Elsevier for the American Society for Reproductive Medicine
      Original Publication: New York, Hoeber.
    • Subject Terms:
      Oocytes* ; Pregnancy* ; Tissue Donors*; Aging/*physiology ; Progesterone/*administration & dosage; Adult ; Female ; Humans ; Infertility, Female/physiopathology ; Infertility, Female/therapy ; Menstrual Cycle ; Middle Aged ; Pessaries ; Progesterone/therapeutic use
    • Abstract:
      Pregnancy rates and implantation rates with oocyte donation in recipients 40 years of age and older were significantly lower than those obtained in recipients under the age of 40. This difference was eliminated when P vaginal suppositories were added to the luteal regimen in older recipients. Our experience suggests that uterine aging may play a role in the successful initiation of a pregnancy, but this may be overcome with the preparation of the uterus with P vaginal suppositories.
    • Accession Number:
      4G7DS2Q64Y (Progesterone)
    • Publication Date:
      Date Created: 19930901 Date Completed: 19931019 Latest Revision: 20190707
    • Publication Date:
      20221213
    • Accession Number:
      10.1016/s0015-0282(16)56179-2
    • Accession Number:
      8375545