Lipid peroxidation, low-level chemiluminescence and regulation of secretion in the mammary gland.

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  • Additional Information
    • Source:
      Publisher: Birkhäuser Verlag Country of Publication: Switzerland NLM ID: 0376547 Publication Model: Print Cited Medium: Print ISSN: 0014-4754 (Print) Linking ISSN: 00144754 NLM ISO Abbreviation: Experientia Subsets: MEDLINE
    • Publication Information:
      Original Publication: Basel, Switzerland : Birkhäuser Verlag
    • Subject Terms:
      Lipid Peroxidation* ; Luminescent Measurements*; Lactation/*physiology ; Mammary Glands, Animal/*metabolism; Acetylcholine/pharmacology ; Animals ; Epinephrine/pharmacology ; Female ; Mammary Glands, Animal/drug effects ; Mice ; Norepinephrine/pharmacology ; Oxytocin/pharmacology ; Thiobarbituric Acid Reactive Substances/metabolism
    • Abstract:
      In mammary explants of lactating mice, changes in the intensity of chemiluminescence (CL) were observed after the addition to the incubation medium of hormones and mediators that are involved in the regulation of secretion: oxytocin, acetylcholine, epinephrine and norepinephrine. A 15-min period of treatment with oxytocin, epinephrine or norepinephrine changed the level of thiobarbituric acid-reactive substances (TBARS). Two mammary explants, one of which was treated with oxytocin, acetylcholine, epinephrine or norepinephrine, were found to interact even when separated by a quartz glass wall. Analysis of the level of TBARS formation in these two explants showed that the observed interactions might be connected with light emission resulting from lipid peroxidation (LP) processes. The possible role of LP and low-level CL in the regulation of mammary gland secretion is discussed.
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    • Accession Number:
      0 (Thiobarbituric Acid Reactive Substances)
      50-56-6 (Oxytocin)
      N9YNS0M02X (Acetylcholine)
      X4W3ENH1CV (Norepinephrine)
      YKH834O4BH (Epinephrine)
    • Publication Date:
      Date Created: 19931015 Date Completed: 19931126 Latest Revision: 20190629
    • Publication Date:
      20240829
    • Accession Number:
      10.1007/BF01952600
    • Accession Number:
      8224103