A complement fixation method for quantitative differentiation of reactions to 45/20 vaccine and Brucella infection.

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  • Author(s): Miller JK; Kelly JI; Roerink JH
  • Source:
    The Veterinary record [Vet Rec] 1976 Mar 13; Vol. 98 (11), pp. 210-5.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Wiley Country of Publication: England NLM ID: 0031164 Publication Model: Print Cited Medium: Print ISSN: 0042-4900 (Print) Linking ISSN: 00424900 NLM ISO Abbreviation: Vet Rec Subsets: MEDLINE
    • Publication Information:
      Publication: 2021- : [Oxford] : Wiley
      Original Publication: -June 2009 : London : British Veterinary Medicine
    • Subject Terms:
      Brucella Vaccine* ; Complement Fixation Tests*; Brucellosis, Bovine/*immunology; Animals ; Antibodies, Bacterial/analysis ; Brucella abortus/immunology ; Brucellosis, Bovine/diagnosis ; Cattle ; Vaccination/veterinary
    • Abstract:
      Brucella complement fixing antibodies may be titrated independently in adult vaccinated (strain 45/20) and in naturally infected cattle by serological tests utilizing a specially prepared antigen. Serum samples are subjected to the standard complement fixation test for the diagnosis of brucellosis (MacKinnon 1963) and subsequently retested by the same method but with a saline extract antigen prepared from strain 45/20 Brucella abortus. The results obtained in the two tests are compared in five specific categories of brucella reactors. An evaluation and discussion of the test method, on the basis of the results obtained, indicates that informed diagnoses can be made in parallel with a continuous adult vaccination programme.
    • Accession Number:
      0 (Antibodies, Bacterial)
      0 (Brucella Vaccine)
    • Publication Date:
      Date Created: 19760313 Date Completed: 19760706 Latest Revision: 20190702
    • Publication Date:
      20240829
    • Accession Number:
      10.1136/vr.98.11.210
    • Accession Number:
      817437