[A review of new cephalosporin antibiotics].

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  • Additional Information
    • Transliterated Title:
      Prehlad novsích cefalosporínových antibiotík.
    • Source:
      Publisher: Ambit Media Country of Publication: Czech Republic NLM ID: 0413602 Publication Model: Print Cited Medium: Print ISSN: 0042-773X (Print) Linking ISSN: 0042773X NLM ISO Abbreviation: Vnitr Lek Subsets: MEDLINE
    • Publication Information:
      Publication: 2010- : Brno : Ambit Media
      Original Publication: 1973-<1994> : Praha : Avicenum
    • Subject Terms:
      Cephalosporins*/chemistry ; Cephalosporins*/pharmacology; Drug Resistance, Microbial
    • Abstract:
      The authors discuss some properties of recent cephalosporin antibiotics and the antibiotics effectiveness in particular of more recent generations of cephalosporins. The increasing resistance to penicillins and other antibiotics called for use effective cephalosporins of new generations. While cephalosporins of the 1st generation (cephalothin, cephazoline, and oral cephaloridine or cephaclor) are effective against Gram-positive bacteria, haemophilus bacteria and Klebsiellae, the resistance of other bacteria even against these antibiotics is increasing. Mephoxine and cephuroxime belong to the 2nd generation as their spectrum of efficiency is wider. Cephalosporins of the 3rd generation (cefotaxime, ceftriaxone, ceftazidime and others) are effective only against strains resistant to cephalosporins of the older generations. Oral preparations of cephalosporins of recent generations (Loracarbef, cefpodoxim, ceftibutene) are also useful.
    • Number of References:
      8
    • Accession Number:
      0 (Cephalosporins)
    • Publication Date:
      Date Created: 19940201 Date Completed: 19940428 Latest Revision: 20061115
    • Publication Date:
      20221213
    • Accession Number:
      8140760