Immunosuppressive activity of sera of pregnant women on cytotoxic T-lymphocyte-mediated cytolysis. I. Characterization of the active fraction.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • Author(s): Letellier C;Letellier C; Fizet D; Baltz T; Vezon G
  • Source:
    Gynecologic and obstetric investigation [Gynecol Obstet Invest] 1994; Vol. 37 (1), pp. 1-5.
  • Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Karger Country of Publication: Switzerland NLM ID: 7900587 Publication Model: Print Cited Medium: Print ISSN: 0378-7346 (Print) Linking ISSN: 03787346 NLM ISO Abbreviation: Gynecol Obstet Invest Subsets: MEDLINE
    • Publication Information:
      Original Publication: Basel, New York, Karger.
    • Subject Terms:
    • Abstract:
      Sera of healthy pregnant women have a nonspecific inhibitory activity on the specific cytolytic activity of activated cytotoxic T lymphocytes in vitro. The serum fraction of pregnant females which is responsible for this activity has been characterized. The equivalent fraction derived from sera of healthy men has a similar but reduced activity compared with the female fraction. This suppressive factor seems to be activated during pregnancy. Moreover, this study sheds some light on the reasons behind the attenuation of the maternal immune system during pregnancy.
    • Accession Number:
      0 (Suppressor Factors, Immunologic)
    • Publication Date:
      Date Created: 19940101 Date Completed: 19940414 Latest Revision: 20180217
    • Publication Date:
      20231215
    • Accession Number:
      10.1159/000292509
    • Accession Number:
      8125399