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[Bile composition and antibiotic excretion. Observations with T-drainage].
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- Author(s): Rosenthal RJ;Rosenthal RJ; Steigerwald SD; Bockhorn H
- Source:
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete [Z Gesamte Inn Med] 1993 Jan; Vol. 48 (1), pp. 18-22.
- Publication Type:
Clinical Trial; Controlled Clinical Trial; English Abstract; Journal Article; Randomized Controlled Trial
- Language:
German
- Additional Information
- Transliterated Title:
Gallenzusammensetzung und Antibiotikaausscheidung. Beobachtungen an der T-Drainage.
- Source:
Publisher: Georg Thieme Country of Publication: Germany NLM ID: 21730470R Publication Model: Print Cited Medium: Print ISSN: 0044-2542 (Print) Linking ISSN: 00442542 NLM ISO Abbreviation: Z Gesamte Inn Med Subsets: MEDLINE
- Publication Information:
Original Publication: Leipzig : Georg Thieme, [1946]-c1993.
- Subject Terms:
- Abstract:
Patients comparable in disease, therapy and serum bilirubin concentration were either treated with mezlocillin intravenously or not at all. The bile of each patient was collected either from a T-drainage or from a percutaneously placed drainage into the bile ducts. The concentrations of GGT and AP, which were liberated by destroyed liver cells, and of bilirubin and mezlocillin, which were secreted actively, were analysed. Those patients who had normal serum bilirubin concentrations had a significantly higher biliary bilirubin excretion than those with high serum bilirubin level. The maximum excretion was after 4 hours. While the biliary concentration of bilirubin decreased, the concentration of secreted mezlocillin increased. Due to destroyed liver cells those patients with pathologically elevated blood bilirubin levels had a 50-fold lower mezlocillin excretion than those with normal blood values.
- Accession Number:
EC 2.3.2.2 (gamma-Glutamyltransferase)
EC 3.1.3.1 (Alkaline Phosphatase)
OH2O403D1G (Mezlocillin)
RFM9X3LJ49 (Bilirubin)
- Publication Date:
Date Created: 19930101 Date Completed: 19930401 Latest Revision: 20131121
- Publication Date:
20221213
- Accession Number:
8095119
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