[Use of levamisole electrophoresis in chemical prophylaxis in adolescents with a change in tuberculin reaction].

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  • Author(s): Sirenko IA; Nastas PN
  • Source:
    Problemy tuberkuleza [Probl Tuberk] 1993 (3), pp. 30-3.
  • Publication Type:
    Comparative Study; English Abstract; Journal Article
  • Language:
    Russian
  • Additional Information
    • Transliterated Title:
      Primenenie élektroforeza levamizola pri khimmioprofilaktike u podrostkov s virazhom tuberkulinovykh reaktsiĭ.
    • Source:
      Publisher: Medit︠s︡ina Country of Publication: Russia (Federation) NLM ID: 0414141 Publication Model: Print Cited Medium: Print ISSN: 0032-9533 (Print) Linking ISSN: 00329533 NLM ISO Abbreviation: Probl Tuberk Subsets: MEDLINE
    • Publication Information:
      Original Publication: Moskva : Medit︠s︡ina, -2003.
    • Subject Terms:
      Iontophoresis* ; Tuberculin Test*; Levamisole/*administration & dosage ; Tuberculosis, Pulmonary/*prevention & control; Adolescent ; Female ; Humans ; Isoniazid/therapeutic use ; Male ; Time Factors ; Tuberculin/immunology
    • Abstract:
      Immunological reactivity was assessed in 108 adolescents aged 12-17: 25 healthy subjects, 29 and 54 adolescents with a turn in tuberculin tests. The latter received isoniazid alone for 3 months and in combination with levamisole electrophoresis, respectively. Immunological reactivity responded more advantageously in 54 subjects exposed to adjuvant levamisole electrophoresis. They showed inhibition of immunospecific reactions and enhancement of nonspecific ones as well as of skin tuberculin sensitivity. Levamisole electrophoresis raised the efficacy of secondary prophylaxis in adolescents with a turn in tuberculin tests.
    • Accession Number:
      0 (Tuberculin)
      2880D3468G (Levamisole)
      V83O1VOZ8L (Isoniazid)
    • Publication Date:
      Date Created: 19930101 Date Completed: 19941230 Latest Revision: 20131121
    • Publication Date:
      20240829
    • Accession Number:
      7984586