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Distribution of complement C'2 and C'6 types in Australian cases of diabetes mellitus.
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- Author(s): Kirk RL; Ranford PR; Court J; Zimmet P
- Source:
The Medical journal of Australia [Med J Aust] 1980 Nov 29; Vol. 2 (11), pp. 614-5.- Publication Type:
Journal Article; Research Support, U.S. Gov't, P.H.S.- Language:
English - Source:
- Additional Information
- Source: Publisher: Australasian Medical Publishing Co Country of Publication: Australia NLM ID: 0400714 Publication Model: Print Cited Medium: Print ISSN: 0025-729X (Print) Linking ISSN: 0025729X NLM ISO Abbreviation: Med J Aust Subsets: MEDLINE
- Publication Information: Publication:
: Pyrmont, NSW : Australasian Medical Publishing Co.
Original Publication: Sydney : Australasian Medical Pub. Co. - Subject Terms:
- Abstract: A series of patients with juvenile onset diabetes (IDDM) and mature onset diabetes (NIDDM) have been typed for genetic variants of two sets of complement factors. For the HLA-linked C'2 system, there was found a significant increase of the C'2 2-1 type in IDDM compared with NIDDM patients or healthy controls. No such increase in any phenotype was observed for the non-HLA-linked C'6 system. These observations emphasize again the genetic distinction between IDDM and NIDDM, and the role of chromosome 6 in controlling susceptibility to the insulin-dependent form of the disease.
- Grant Information: R01 AM25446 United States AM NIADDK NIH HHS
- Accession Number: 0 (Complement C2)
0 (Complement C6)
0 (HLA Antigens) - Publication Date: Date Created: 19801129 Date Completed: 19810424 Latest Revision: 20210107
- Publication Date: 20221213
- Accession Number: 10.5694/j.1326-5377.1980.tb77064.x
- Accession Number: 7464619
- Source:
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