Clearance of inflammatory cells from the microcirculation of endotoxin-resistant C3H/HeJ mice.

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  • Author(s): Walker RI; Parker GA
  • Source:
    Canadian journal of microbiology [Can J Microbiol] 1980 Jun; Vol. 26 (6), pp. 725-7.
  • Publication Type:
    Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 0372707 Publication Model: Print Cited Medium: Print ISSN: 0008-4166 (Print) Linking ISSN: 00084166 NLM ISO Abbreviation: Can J Microbiol Subsets: MEDLINE
    • Publication Information:
      Publication: 2011- : Ottawa, ON : Canadian Science Publishing
      Original Publication: Ottawa, Canada : National Research Council, [1954-
    • Subject Terms:
      Blood Platelets* ; Neutrophils* ; Salmonella typhi*; Endotoxins/*pharmacology ; Lung/*blood supply; Animals ; Capillaries/cytology ; Drug Resistance ; Leukopenia ; Mice ; Mice, Inbred C3H ; Thrombocytopenia
    • Abstract:
      We studied the deposition of platelets and leukocytes in resistant (C3H/HeJ) and sensitive (C3Heb/FeJ) strains of mice challenged intraperitoneally with 1 mg of Salmonella typhi endotoxin, a dose lethal only for the sensitive strain. Comparable degrees of leukopenia and thrombocytopenia were evident at all time periods observed, but in contrast to sensitive mice, leukocytes and platelets were quickly cleared from the pulmonary microcirculation of resistant mice.
    • Accession Number:
      0 (Endotoxins)
    • Publication Date:
      Date Created: 19800601 Date Completed: 19801027 Latest Revision: 20190720
    • Publication Date:
      20240829
    • Accession Number:
      10.1139/m80-125
    • Accession Number:
      7397612