SÍNDROME SEROTONÍNICO PEDIÁTRICO. REPORTE DE UN CASO.

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    • Abstract:
      El síndrome serotoninico es un cuadro neurologico agudo debido a hiperactividad serotoninérgica, por la interacción de drogas que refuerzan o mimetizan la acción del neurotrasmisor. La incidencia del sindrome de serotonina es ascendente por Ia disponibilidad creciente de fármacos serotoninérgicos como los antidepresivos. Por ello es importante que los medicos reconozcan y manejen adecuadamente ci sindrome serotoninico. Este reporte de caso se refiere a una intoxicación accidental por ci neuroléptico atipico oIanzapina en un niño de 2 altos, quien desarrolió manifestaciones cilnicas como agltación, sudoración, mioclonlas, cionus espontáneo e hipertermia, considerados como criterios diagnóstico del cuadro. La terapia consistió en descontaminación intema con iavado gástrico, carbóñ activado y sulfato de sodio, ciproheptadina, propranolol y furosemida. Su evolución fue satisfactoria. En nuestro pais hay disponibilidad de la mayoria de los fármacos causales y tienen amplio uso, por lo que es probable el subregistro del sindrome. Dc alli la importancia de este reporte de caso. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Serotonin syndrome is an acute neurologic picture due to serotonergic hyperactivity, due to the interaction of drugs that enhance or mimic the action of the serotonin. The incidence of serotonin syndrome is rising because of the growing availability of serotonergic drugs such as antidepressants. It is therefore important that clinicians recognize and manage appropriately this syndrome. This case report refers to an accidental poisoning by the atypical neuroleptic olanzapine in a 2 year old boy who developed clinical manifestations such as agitation, sweating, myoclonus, spontaneous clonus and hyperthermia, considered as diagnostic criteria for the syndrome. Therapy consisted of internal decontamination with gastric lavage, activated charcoal and sodium sulfate, cyproheptadine, propranolol and furosemide. The clinical outcome was satisfactory. In our country the majority of the causal drugs are easily available and widely employed, for which reason it is probable that this syndrome is under registered. Hence the importance of this case report. [ABSTRACT FROM AUTHOR]
    • Abstract:
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