Hyperoxie normobarique chez le patient traumatisé crânien

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    • Alternate Title:
      Normobaric hyperoxia therapy for patients with traumatic brain injury
    • Abstract:
      Abstract: Cerebral ischaemia plays a major role in the outcome of brain-injured patients. Because brain oxygenation can be assessed at bedside using intra-parenchymal devices, there has been a growing interest about whether therapeutic hyperoxia could be beneficial for severely head-injured patients. Normobaric hyperoxia increases brain oxygenation and may improve glucose-lactate metabolism in brain regions at risk for ischaemia. However, benefits of normobaric hyperoxia on neurological outcome are not established yet, that hinders the systematic use of therapeutic hyperoxia in head-injured patients. This therapeutic option might be proposed when brain ischemia persists despite the optimization of cerebral blood flow and arterial oxygen blood content. [Copyright &y& Elsevier]
    • Abstract:
      Résumé: Un regain d’intérêt pour l’hyperoxie thérapeutique normobare chez le patient traumatisé crânien a été observé récemment, à la faveur de l’utilisation croissante du monitorage de la pression tissulaire cérébrale en oxygène et de la recherche de nouvelles modalités neuroprotectrices luttant contre l’ischémie cérébrale. Il est indéniable que l’hyperoxie augmente l’oxygénation cérébrale et améliore le métabolisme aérobie dans les zones à risque d’ischémie cérébrale. Cependant, le bénéfice de l’hyperoxie sur le plan neurologique n’est pas établi et ne permet pas de recommander l’usage de l’hyperoxie thérapeutique en routine clinique. L’hyperoxie normobare pourrait avoir un intérêt chez les patients à risque ischémique persistant malgré l’optimisation du débit sanguin cérébral et du contenu artériel en oxygène.
    • Abstract:
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