Plasma levels of norethidrone in Indian women receiving norethidrone enanthate (20 mg) injectable.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: United States NLM ID: 0234361 Publication Model: Print Cited Medium: Print ISSN: 0010-7824 (Print) Linking ISSN: 00107824 NLM ISO Abbreviation: Contraception Subsets: MEDLINE
    • Publication Information:
      Publication: New York : Elsevier
      Original Publication: Los Altos, Calif., Geron-X.
    • Subject Terms:
    • Abstract:
      Plasma norethindrone (NET) and progesterone were estimated by radioimmunoassay in seven Indian women after intramuscular administration of 20 mg NET enanthate. One subject had intermenstrual bleeding throughout the cycle. Out of the six subjects considered for analysis, three subjects showed ovulation suppression, two had delayed ovulation and the remaining one exhibited normal ovulatory pattern. Post-peak average plasma NET values ranged from 1.0 to 2.1 ng/ml. These values showed a significant positive correlation with the anthropometric indices such as body weight and mid-arm-circumference. The subjects with lower anthropometry showed exponential decline of plasma NET. A possible role for nutritional status of an individual in drug disposition is indicated from this study.
    • Accession Number:
      4G7DS2Q64Y (Progesterone)
      HY3S2K0J0F (norethindrone enanthate)
      T18F433X4S (Norethindrone)
    • Publication Date:
      Date Created: 19810501 Date Completed: 19811215 Latest Revision: 20190825
    • Publication Date:
      20250114
    • Accession Number:
      10.1016/0010-7824(81)90077-9
    • Accession Number:
      7285573