Classes of Depression, Anxiety, and Functioning in Acute Coronary Syndrome Patients.

Objectives: To describe change in subgroups characterized by patterns of depression, anxiety, and functional impairment; examine treatment effects on subgroup membership; examine effects of sex and age on subgroup membership. Methods: Latent class models were used to meet the first 2 objectives using 79 patients with depression/anxiety. Generalized estimating equations were used to meet the third objective. Results: Three subgroups characterized by different combinations of psychiatric disorders and functioning were identified. Patients who received treatment were more likely to transition to a less impaired subgroup. Conclusions: Unique information about holistic treatment effects can be gained when multiple outcomes are considered simultaneously. [ABSTRACT FROM AUTHOR]

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