Deferiprone: greater efficacy at depleting myocardial than hepatic iron?

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    • Subject Terms:
      CHELATION therapy; IRON in the body; DEFEROXAMINE; METALS in the body
    • Abstract:
      Comments on the efficacy of deferiprone in replacing desferrioxamine for the treatment of iron-overload disease. Mention of a study in this issue by Lisa Anderson and colleagues which reports on the effects of deferiprone and desferrioxamine on hepatic and myocardial concentrations of iron and left-ventricular function; Commentary on iron chelation therapy.