Gene expression profiling in breast cancer: classification, prognostication, and prediction.

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    • Abstract:
      The article discusses the significance of microarray-based gene expression profiling in breast cancer. It mentions that studies of gene expression profiling have shown that oestrogen-receptor (ER)-positive and ER-negative breast cancers are distinct diseases at the transcriptomic level. It focuses on the conceptual effect and potential clinical use of the molecular classification of breast cancer and discusses its predictive multigene predictors.