Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling.

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    • Abstract:
      Examines the prickle mediation feedback amplification to generate asymmetric planar cell polarity signaling. Response to aggregated cells of Dictyostelium to chemoattractants; Prediction on the loss of Fz in the feedback loop model in the neighboring distal cells causing reverse polarity.