It's enough to give you HEARTBURN.

PROTON pump inhibitors; HEARTBURN; BACTERIAL diseases; CLOSTRIDIOIDES difficile; GUT microbiome; DRUG prescribing; THERAPEUTICS

The article discusses proton pump inhibitors (PPIs), which are used for the treatment of heartburn. According to the author, PPIs are one of the most effective acid reflux drugs, but they may pose health risks, such as bacterial infections. Topics include an overview of the microbiology of the human gastrointestinal system, infection from the bacterium Clostridium difficile in patients taking PPIs, and statistics related to the overprescription of PPIs globally.