Regulation of the Pulmonary Circulation in the Fetus and Newborn.

The article discusses the physiological regulations of the fetal and newborn pulmonary circulation. It says that the regulation allows development on air passing the lungs for breathing dominated by the mitogenic factors. It states that the advancement in understanding the perinatal pulmonary circulation had contributed to the persistent pulmonary hypertension of the newborn (PPHN) treatment like rho kinase (ROK) inhibitors that are proven effective, however, have side effects left undiscovered.