Basal ganglia cellular pathology in multiple system atrophy, progressive supranuclear palsy and Parkinson disease. Can quantitative magnetic resonance spectroscopic imaging make the difference?

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    • Subject Terms:
      MAGNETIC resonance imaging; SYMPTOMATIC Parkinson's disease; PROGRESSIVE supranuclear palsy; ATROPHY
    • Abstract:
      The authors reflect on the study of Guevara and colleagues on the use of magnetic resonance spectroscopic imaging (MRI) to patients with Parkinson diseases (APD). The authors explore the MRI use to parkinsonian disorder patients such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). They add that the MRI shows the lower N-acetylaspartate (NAA) concentrations in the lentiform nucleus and pallidum indcating its ability for basal ganglia cellular pathology quantification.