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Phone: (843) 766-6635
Folly Beach Library
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Edgar Allan Poe/Sullivan's Island Library
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Wando Mount Pleasant Library
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Phone: (843) 805-6888
Village Library
9 a.m. - 1 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. - 8 p.m.
Phone: (843) 889-3300
Otranto Road Library
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McClellanville Library
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Keith Summey North Charleston Library
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Hurd/St. Andrews Library
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Dorchester Road Library
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Phone: (843) 805-6930
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Affects of ionizing radiation on T-cell population lymphocyte: A risk factor of Irritable Bowel Syndrome.
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- Author(s): Sheikh Sajjadieh, M. R.; Kuznetsova, L. V.; Bojenko, V. B.
- Source:
Toxicology & Industrial Health; Jul2010, Vol. 26 Issue 6, p323-330, 8p, 4 Charts, 2 Graphs- Subject Terms:
- Source:
- Additional Information
- Subject Terms:
- Abstract: Irritable bowel syndrome is observed mostly in Ukrainian children and may be related to adverse health effects as a result of the Chernobyl disaster. The aim of this study was to determine status of T-cell population lymphocytes in children with clinical symptom of irritable bowel syndrome. The test population consisted of 95 participants: 75 rural patients aged 4 to 18 who lived in a contaminated area exposed to natural environmental radiation with clinical symptom of irritable bowel syndrome (categorized in three groups) and 20 healthy urban participants from Kiev aged 5 to 15 as control group. Internal radiation activity has been measured by γ-ray spectrometry. Peripheral blood leukocytes were analyzed for T-lymphocytes subset such as T-lymphocytes (CD3+), T-helper (CD4+) and T-cytotoxic (CD8+ and then CD4/CD8 ratio was calculated. Percentage of CD3+ and CD4+ in all study groups decreased significantly in comparison to control group (p < 0.001). Percentage of CD8+ increased significantly in all study groups in comparison to control group (p < 0.05). The CD4/CD8 ratio decreased significantly all study groups in comparison to control group (p < 0.001). Cellular immune status of study groups that are residing in a contaminated area has changed. Our data have demonstrated that this change may be related to a higher incidence of children with irritable bowel syndrome. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Toxicology & Industrial Health is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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