Quantitation of immunoglobulin-bearing lymphocytes and lymphocyte response to mitogens in horses persistently infected by equine infectious anemia virus.

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  • Author(s): Banks KL; Henson JB
  • Source:
    Infection and immunity [Infect Immun] 1973 Oct; Vol. 8 (4), pp. 679-82.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Print Cited Medium: Print ISSN: 0019-9567 (Print) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE
    • Publication Information:
      Publication: Washington, DC : American Society For Microbiology
      Original Publication: [Bethesda, Md.] American Society for Microbiology.
    • Subject Terms:
      Equine Infectious Anemia/*immunology ; Immunoglobulins/*analysis ; Lymphocyte Activation/*drug effects ; Lymphocytes/*immunology ; Mitogens/*pharmacology; Animals ; Fluorescent Antibody Technique ; Goats/immunology ; Horses ; Immune Sera ; Lectins/pharmacology
    • Abstract:
      A defect in lymphocyte function could be responsible for persistent infection by the equine infectious anemia virus. The number of lymphocytes bearing surface immunoglobulin, as detected by immunofluorescence, and lymphocyte response to mitogens were the same in uninfected and equine infectious anemia-infected animals. A defect in T or B lymphocyte numbers or ability to respond to stimuli was not detected in this chronic virus disease.
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    • Accession Number:
      0 (Immune Sera)
      0 (Immunoglobulins)
      0 (Lectins)
      0 (Mitogens)
    • Publication Date:
      Date Created: 19731001 Date Completed: 19731212 Latest Revision: 20210526
    • Publication Date:
      20231215
    • Accession Number:
      PMC422911
    • Accession Number:
      10.1128/iai.8.4.679-682.1973
    • Accession Number:
      4582640