Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4-alpha.

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    • Subject Terms:
      FATTY acids; LIVER cells; PHYSIOLOGY; CYTOCHEMISTRY
    • Abstract:
      Presents research which studied how long-chain fatty acids directly modulate the transcriptional activity of hepatocyte nuclear factor-4-alpha (HNF-4-alpha). Modulation of various diseases by dietary fatty acids; Effects of fatty acids in disease depending on chain length and degree of saturation; Other roles for fatty acids; Expression of HNF-4-alpha-controlled genes.