Articular manifestations in inflammatory bowel disease patients: A prospective study.

Abstract: Background and aims: Rheumatic manifestations are frequent in inflammatory bowel disease (IBD) and are associated with a wide range of clinical patterns. Methods: Articular symptoms and signs were investigated by questionnaire in a cohort of 651 pts, mean age 42±14 years, followed at two referral hospitals over a 12-month period. Results: 142 ulcerative colitis (UC) and 120 Crohn''s disease (CD) patients referred articular pain during their IBD history: in 46% this was associated with active IBD, in 56% symptoms were intermittent and in 19% symptoms preceded IBD diagnosis. 62 pts (28 UC, 34 CD) complaining of articular symptoms at the time of the interview, were investigated by the rheumatologist: arthropathy was axial in 52%, oligoarticular in 16% and polyarticular in 23%. Oligoarthritis commonly involved the lower limbs and was more commonly associated with UC. The mean number of small joints involved was significantly higher in CD than in UC pts (9.9±8.2 vs. 5.6±4.3; p <0.01). Bone scintigraphy was abnormal in 70% of pts. Conclusions: Prevalence of self-reported articular symptoms in IBD patients exceeds 40% with 9.5% incidence during 1-year follow up. Symptoms predict entheropatic involvement of the locomotor system. [Copyright &y& Elsevier]

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