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The treatment of challenging behaviour in intellectual disabilities: cost-effectiveness analysis.
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- Author(s): Romeo, R. (AUTHOR); Knapp, M. (AUTHOR); Tyrer, P. (AUTHOR); Crawford, M. (AUTHOR); Oliver‐Africano, P. (AUTHOR)
- Source:
Journal of Intellectual Disability Research. Jul2009, Vol. 53 Issue 7, p633-643. 11p. 3 Charts, 2 Graphs. - Source:
- Additional Information
- Subject Terms:
- Subject Terms:
- Abstract: Background Antipsychotic drugs are used in the routine treatment of adults with intellectual disabilities (ID) and challenging behaviour in the UK despite limited evidence of their effectiveness. There is no evidence on their cost-effectiveness. Methods The relative cost-effectiveness of risperidone, haloperidol and placebo in treating individuals with an ID and challenging behaviour was compared from a societal perspective in a 26-week, double-blind, randomised controlled trial. Outcomes were changes in aggression and quality of life. Costs measured all service impacts and unpaid caregiver inputs. Results After 26 weeks, patients randomised to placebo had lower costs compared with those in the risperidone and haloperidol treatment groups. Aggression was highest for patients treated with risperidone and lowest for patients treated with haloperidol; however, quality of life was lowest for patients treated with haloperidol and highest for patients treated with risperidone. Conclusion The treatment of challenging behaviour in ID with antipsychotic drugs is not a cost-effective option. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of Intellectual Disability Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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