Tonsils: the next frontier in the treatment of palmoplantar pustulosis.

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  • Additional Information
    • Source:
      Publisher: John Libbey Eurotext Country of Publication: France NLM ID: 9206420 Publication Model: Print Cited Medium: Internet ISSN: 1952-4013 (Electronic) Linking ISSN: 11671122 NLM ISO Abbreviation: Eur J Dermatol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Montrouge, France : John Libbey Eurotext, c1991-
    • Subject Terms:
      Palatine Tonsil*/pathology ; Palatine Tonsil*/surgery ; Psoriasis*/therapy ; Tonsillectomy*; Humans
    • Abstract:
      Palmoplantar pustulosis (PPP) is a chronic relapsing inflammatory disease of unknown aetiology characterized by erythema, scaling, and aseptic pustules, which pose a significant clinical, psychological, and economic burden to patients. Studies have shown that the tonsils play a key role in the exacerbation and pathogenesis of certain diseases. This paper systematically summarizes the evidence supporting the close association between tonsils and PPP, and proposes mechanisms by which tonsils may contribute to the pathogenesis of PPP. In addition, the paper elucidates the role of tonsillectomy in alleviating PPP, provides a basis for considering it as a treatment option after conventional PPP treatment has failed, and lays the groundwork for an in-depth investigation of the intricate relationship between tonsillectomy and PPP.
    • Contributed Indexing:
      Keywords: palmoplantar pustulosis; tonsillectomy; tonsils; treatment
    • Publication Date:
      Date Created: 20241126 Date Completed: 20241126 Latest Revision: 20241203
    • Publication Date:
      20241204
    • Accession Number:
      10.1684/ejd.2024.4748
    • Accession Number:
      39589028