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Congenital Plasmodium vivax in a 3-day-old neonate: a case report.
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- Additional Information
- Source:
Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE
- Publication Information:
Original Publication: [London] : BioMed Central, [2007-
- Subject Terms:
- Abstract:
Background: Congenital malaria is an uncommon clinical infectious disease caused by vertical transmission of parasites from mother to child during pregnancy or delivery and a positive blood smear of malaria in newborns from 24 hours to 7 days of life, associated with a high mortality rate if it is not diagnosed and treated early. We present an unusual case of a 4-day-old boy with Plasmodium vivax malaria from Gondar, Ethiopia, suspected mainly based on a positive maternal history of malaria attacks in the seventh month of gestation and cured with artemether-lumefantrine therapy. The newborn presented with a lack of sucking and a high-grade fever. The blood film of the baby showed a trophozoite stage of Plasmodium vivax with a parasite density of +2. The neonate had severe thrombocytopenia (76,000/μL) and splenomegaly (the spleen was palpable 2 cm along the growth line). The patient was admitted to the hospital and was treated with artesunate and artemether-lumefantrine.
Conclusion: Most of the Amhara zones are endemic for malaria, and newborns born to mothers in malaria areas or those with a history of malaria attacks in the index pregnancy should be investigated early for malaria rather than treated with sepsis or meningitis. It is wise to consider congenital malaria as part of neonatal sepsis-like presentations, especially if there is a maternal history of malaria attack during pregnancy and if the neonates fully recover.
Competing Interests: Declarations. Ethics approval and consent to participate: Ethical clearance was obtained from the Wallaga University Referral Research Ethics Review Committee. The study protocol is carried out according to the relevant guidelines. Consent for publication: Written informed consent was obtained from the patient's legal guardian for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Competing interests: The authors declare that they have no competing interests.
(© 2024. The Author(s).)
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- Contributed Indexing:
Keywords: Plasmodium vivax; Case report; Congenital malaria; Ethiopia
- Accession Number:
0 (Antimalarials)
0 (Artemether, Lumefantrine Drug Combination)
60W3249T9M (Artesunate)
0 (Artemisinins)
- Publication Date:
Date Created: 20241122 Date Completed: 20241122 Latest Revision: 20241220
- Publication Date:
20241220
- Accession Number:
PMC11583463
- Accession Number:
10.1186/s13256-024-04879-4
- Accession Number:
39574171
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