Onset of ANCA-positive EGPA with bilateral pleural effusion: a case report.

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  • Additional Information
    • Source:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 0351014 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-4877 (Electronic) Linking ISSN: 03007995 NLM ISO Abbreviation: Curr Med Res Opin Subsets: MEDLINE
    • Publication Information:
      Publication: 1995- : Newbury, Berkshire, U.K. : Informa Healthcare
      Original Publication: London, M. D. Promotions, ltd.
    • Subject Terms:
      Pleural Effusion*/etiology ; Antibodies, Antineutrophil Cytoplasmic*/blood ; Antibodies, Antineutrophil Cytoplasmic*/immunology; Humans ; Male ; Churg-Strauss Syndrome/complications ; Churg-Strauss Syndrome/diagnosis ; Churg-Strauss Syndrome/pathology ; Churg-Strauss Syndrome/drug therapy ; Middle Aged ; Female ; Methylprednisolone/therapeutic use ; Methylprednisolone/administration & dosage
    • Abstract:
      Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic, immune-mediated disease that occurs in patients with asthma and eosinophilia. It is characterized by inflammation of small- and medium-caliber blood vessels.
      Case Report: This report presents an unusual clinical case of EGPA with positive anti-neutrophil cytoplasmic antibodies who manifested bilateral pleural effusion. The diagnosis was confirmed through laboratory assessments and bronchial biopsies. The patient was treated with methylprednisolone showing improvement in symptoms.
      Conclusions: Our case appear interesting considering the limited evidence of pleural effusion in patients with EGPA documented in the literature.
    • Contributed Indexing:
      Keywords: ANCA; EGPA; inflammation; pleural effusion; vasculitis
    • Accession Number:
      0 (Antibodies, Antineutrophil Cytoplasmic)
      X4W7ZR7023 (Methylprednisolone)
    • Publication Date:
      Date Created: 20241108 Date Completed: 20241212 Latest Revision: 20241212
    • Publication Date:
      20241212
    • Accession Number:
      10.1080/03007995.2024.2427882
    • Accession Number:
      39514413