Robotic versus laparoscopic revision to Toupet fundoplication for failed Nissen fundoplication: a single-center experience.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • Additional Information
    • Source:
      Publisher: Springer Country of Publication: England NLM ID: 101300401 Publication Model: Electronic Cited Medium: Internet ISSN: 1863-2491 (Electronic) Linking ISSN: 18632483 NLM ISO Abbreviation: J Robot Surg Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : Springer
    • Subject Terms:
    • Abstract:
      Nissen fundoplication (NF) is a common surgical procedure to treat gastroesophageal reflux disease; however, a subset of patients may continue to experience symptoms or develop symptom recurrence despite a successful procedure. This study aims to compare laparoscopic and robotic approaches for treating failed NF and evaluate the outcomes after converting to Toupet fundoplication (TF). We conducted a retrospective analysis of patients who underwent robotic or laparoscopic revision to TF for failed NF between 2016 and 2023. The data collected included demographics, pre-operative workup, and peri- and post-operative outcomes. Symptom analysis and anti-reflux medication usage were collected using a patient questionnaire. Failed fundoplication was defined as the need for an additional operation due to unresolved GERD symptoms or the emergence of a new issue. Eighty-eight patients (56 laparoscopic, 32 robotic) were included. Mean operative time was 148.71 ± 53.64 min for the total cohort and was significantly longer in the robotic group (RG) 167.43 min vs 138.01 min in the Laparoscopic group (LG) (p value = 0.012). The LG had a length of hospital stay of 2.16 ± 1.69 days vs RG 2.21 ± 1.28 days (p value = 0.867). The LG had a higher number of early readmissions (5.4%, p value = 0.629) and both the LG and the RG had 1 patient that required an early reintervention. Symptoms of dysphagia and reflux decreased in both groups at last follow-up, but the reduction in PPI use was not significant. Surgical revision to TF for failed NF provides significant symptom improvement with low rates of complications and recurrences. Our study shows that both approaches are safe and feasible and have comparable surgical and symptom outcomes.
      (© 2024. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.)
    • References:
      Clarrett DM, Hachem C (2018) Gastroesophageal reflux disease (GERD). Mo Med 115(3):214–218. (PMID: 302287256140167)
      Furnée EJB (2008) Surgical reintervention after antireflux surgery for gastroesophageal reflux disease: a prospective cohort study in 130 Patients. Arch Surg 143(3):267. https://doi.org/10.1001/archsurg.2007.50. (PMID: 10.1001/archsurg.2007.5018347274)
      Hunter JG, Smith CD, Branum GD et al (1999) Laparoscopic fundoplication failures: patterns of failure and response to fundoplication revision. Ann Surg 230(4):595. https://doi.org/10.1097/00000658-199910000-00015. (PMID: 10.1097/00000658-199910000-00015105227291420908)
      Fuchs KH, Breithaupt W, Varga G, Babic B, Eckhoff J, Meining A (2022) How effective is laparoscopic redo-antireflux surgery? Dis Esophagus 35(3):doab091. https://doi.org/10.1093/dote/doab091. (PMID: 10.1093/dote/doab09134969079)
      Schwameis K, Zehetner J, Rona K et al (2017) Post-Nissen dysphagia and bloating syndrome: outcomes after conversion to toupet fundoplication. J Gastrointest Surg 21(3):441–445. https://doi.org/10.1007/s11605-016-3320-y. (PMID: 10.1007/s11605-016-3320-y27834011)
      Funch-Jensen P, Bendixen A, Iversen MG, Kehlet H (2008) Complications and frequency of redo antireflux surgery in Denmark: a nationwide study, 1997–2005. Surg Endosc 22(3):627–630. https://doi.org/10.1007/s00464-007-9705-y. (PMID: 10.1007/s00464-007-9705-y18071800)
      Pennathur A, Awais O, Luketich JD (2010) minimally invasive redo antireflux surgery: lessons learned. Ann Thorac Surg 89(6):S2174–S2179. https://doi.org/10.1016/j.athoracsur.2010.03.077. (PMID: 10.1016/j.athoracsur.2010.03.07720494005)
      Munie S, Nasser H, Gould JC (2019) Salvage options for fundoplication failure. Curr Gastroenterol Rep 21(9):41. https://doi.org/10.1007/s11894-019-0709-2. (PMID: 10.1007/s11894-019-0709-231346780)
      Antiporda M, Jackson C, Smith CD, Thomas M, Elli EF, Bowers SP (2019) Strategies for surgical remediation of the multi-fundoplication failure patient. Surg Endosc 33(5):1474–1481. https://doi.org/10.1007/s00464-018-6429-0. (PMID: 10.1007/s00464-018-6429-030209604)
      Lopes SO, Gonçalves AR, Macedo G, Santos-Antunes J (2023) Endoscopic treatment of gastroesophageal reflux: a narrative review. Porto Biomed J 8(4):e226. https://doi.org/10.1097/j.pbj.0000000000000226. (PMID: 10.1097/j.pbj.00000000000002263754770710400068)
      Saino G, Bonavina L, Lipham JC, Dunn D, Ganz RA (2015) Magnetic sphincter augmentation for gastroesophageal reflux at 5 years: final results of a pilot study show long-term acid reduction and symptom improvement. J Laparoendosc Adv Surg Tech A 25(10):787–792. https://doi.org/10.1089/lap.2015.0394. (PMID: 10.1089/lap.2015.0394264370274624249)
      Salman MA, Salman A, Shaaban HED et al (2023) Nissen versus toupet fundoplication for gastro-oesophageal reflux disease, short and long-term outcomes. a systematic review and meta-analysis. Surg Laparosc Endosc Percutaneous Tech 33(2):171–183. https://doi.org/10.1097/SLE.0000000000001139. (PMID: 10.1097/SLE.0000000000001139)
      Bramhall SR, Mourad MM (2019) Wrap choice during fundoplication. WJG 25(48):6876–6879. https://doi.org/10.3748/wjg.v25.i48.6876. (PMID: 10.3748/wjg.v25.i48.6876319083916938727)
      Granderath FA, Kamolz T, Granderath UM, Pointner R (2007) Gas-related symptoms after laparoscopic 360 degrees Nissen or 270 degrees Toupet fundoplication in gastro-oesophageal reflux disease patients with aerophagia as comorbidity. Dig Liver Dis 39(4):312–318. https://doi.org/10.1016/j.dld.2006.11.011. (PMID: 10.1016/j.dld.2006.11.01117306636)
      Lee TG, Lee IS, Kim BS, Jung HY, Choi YB (2019) Surgical outcomes and over one-year follow-up results of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: single-center experiences. Asian J Surg 42(4):557–562. https://doi.org/10.1016/j.asjsur.2018.09.003. (PMID: 10.1016/j.asjsur.2018.09.00330316665)
      Frazzoni M, Conigliaro R, Colli G, Melotti G (2012) Conventional versus robot-assisted laparoscopic Nissen fundoplication: a comparison of postoperative acid reflux parameters. Surg Endosc 26(6):1675–1681. https://doi.org/10.1007/s00464-011-2091-5. (PMID: 10.1007/s00464-011-2091-522179476)
      Chapman WHH, Young JA, Albrecht RJ, Kim VB, Nifong LW, Chitwood WR (2001) Robotic nissen fundoplication: alternative surgical technique for the treatment of gastroesophageal reflux disease. J Laparoendosc Adv Surg Tech 11(1):27–30. https://doi.org/10.1089/10926420150502904. (PMID: 10.1089/10926420150502904)
      Huttman MM, Robertson HF, Smith AN et al (2022) A systematic review of robot-assisted anti-reflux surgery to examine reporting standards. J Robotic Surg 17(2):313–324. https://doi.org/10.1007/s11701-022-01453-2. (PMID: 10.1007/s11701-022-01453-2)
      Luberice K, Ross S, Crespo K et al (2021) Robotic complex fundoplication in patients at high-risk to fail. JSLS 25(2):e2020.00111. https://doi.org/10.4293/JSLS.2020.00111. (PMID: 10.4293/JSLS.2020.00111342483338241286)
      Hunter JG, Smith CD, Branum GD et al (1999) Laparoscopic fundoplication failures. Ann Surg 230(4):595. (PMID: 10.1097/00000658-199910000-00015105227291420908)
      Soper NJ, Dunnegan D (1999) Anatomic fundoplication failure after laparoscopic antireflux surgery. Ann Surg 229(5):669–676. https://doi.org/10.1097/00000658-199905000-00009. (PMID: 10.1097/00000658-199905000-00009102355251420811)
      Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications. Ann Surg 240(2):205–213. https://doi.org/10.1097/01.sla.0000133083.54934.ae. (PMID: 10.1097/01.sla.0000133083.54934.ae152735421360123)
      Sheetz KH, Claflin J, Dimick JB (2020) Trends in the adoption of robotic surgery for common surgical procedures. JAMA Netw Open 3(1):e1918911. https://doi.org/10.1001/jamanetworkopen.2019.18911. (PMID: 10.1001/jamanetworkopen.2019.18911319225576991252)
      Napolitano MA, Zebley JA, Wagner K et al (2022) Robotic foregut surgery in the veterans health administration: increasing prevalence, decreasing operative time, and improving outcomes. J Am Coll Surg 235(2):149–156. https://doi.org/10.1097/XCS.0000000000000218. (PMID: 10.1097/XCS.000000000000021835839388)
      Shao JM, Elhage SA, Prasad T et al (2021) Best reoperative strategy for failed fundoplication: redo fundoplication or conversion to Roux-en-Y gastric diversion? Surg Endosc 35(7):3865–3873. https://doi.org/10.1007/s00464-020-07800-4. (PMID: 10.1007/s00464-020-07800-432676728)
      Mittal SK, Légner A, Tsuboi K, Juhasz A, Bathla L, Lee TH (2013) Roux-en-Y reconstruction is superior to redo fundoplication in a subset of patients with failed antireflux surgery. Surg Endosc 27(3):927–935. https://doi.org/10.1007/s00464-012-2537-4. (PMID: 10.1007/s00464-012-2537-423052516)
      Draaisma WA, Ruurda JP, Scheffer RCH et al (2006) Randomized clinical trial of standard laparoscopic versus robot-assisted laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease. Br J Surg 93(11):1351–1359. https://doi.org/10.1002/bjs.5535. (PMID: 10.1002/bjs.553517058295)
      Markar SR, Karthikesalingam AP, Hagen ME, Talamini M, Horgan S, Wagner OJ (2010) Robotic vs. laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease: systematic review and meta-analysis. Int J Med Robot. 6(2):125–131. https://doi.org/10.1002/rcs.309. (PMID: 10.1002/rcs.30920506440)
      Tolboom RC, Draaisma WA, Broeders IAMJ (2016) Evaluation of conventional laparoscopic versus robot-assisted laparoscopic redo hiatal hernia and antireflux surgery: a cohort study. J Robotic Surg 10(1):33–39. https://doi.org/10.1007/s11701-016-0558-z. (PMID: 10.1007/s11701-016-0558-z)
      Giovannetti A, Craigg D, Castro M, Ross S, Sucandy I, Rosemurgy A (2019) Laparoendoscopic single-site (LESS) versus robotic “Redo” hiatal hernia repair with fundoplication: which approach is better? Am Surg 85(9):978–984. (PMID: 10.1177/00031348190850093931638510)
      Al Hashmi AW, Pineton de Chambrun G, Souche R et al (2019) A retrospective multicenter analysis on redo-laparoscopic anti-reflux surgery: conservative or conversion fundoplication? Surg Endosc 33(1):243–251. https://doi.org/10.1007/s00464-018-6304-z. (PMID: 10.1007/s00464-018-6304-z29943063)
      Koch OO, Kaindlstorfer A, Antoniou SA, Asche KU, Granderath FA, Pointner R (2012) Laparoscopic Nissen versus Toupet fundoplication: objective and subjective results of a prospective randomized trial. Surg Endosc 26(2):413–422. https://doi.org/10.1007/s00464-011-1889-5. (PMID: 10.1007/s00464-011-1889-521898012)
      Chao TZ, Wang B, Xiang SC, Zhang W, Jiang DZ, Qiu M (2015) A meta-analysis of randomized controlled trials to compare long-term outcomes of nissen and toupet fundoplication for gastroesophageal reflux disease. PLoS One. 10(6):e0127627. https://doi.org/10.1371/journal.pone.0127627. (PMID: 10.1371/journal.pone.0127627)
      Peristeri DV, Room H, Tsironis D, Vasilikostas G, Wan A (2023) Long-term efficacy of total versus posterior partial fundoplication in patients with gastro-oesophageal reflux disease: a systematic review and meta-analysis. Ann R Coll Surg Engl. https://doi.org/10.1308/rcsann.2023.0046. (PMID: 10.1308/rcsann.2023.00463784309511365733)
      Analatos A, Lindblad M, Ansorge C, Lundell L, Thorell A, Håkanson BS (2022) Total versus partial posterior fundoplication in the surgical repair of para-oesophageal hernias: randomized clinical trial. BJS Open. 6(3):zrac034. https://doi.org/10.1093/bjsopen/zrac034. (PMID: 10.1093/bjsopen/zrac034355110519070466)
      Tan G, Yang Z, Wang Z (2011) Meta-analysis of laparoscopic total (Nissen) versus posterior (Toupet) fundoplication for gastro-oesophageal reflux disease based on randomized clinical trials. ANZ J Surg 81(4):246–252. https://doi.org/10.1111/j.1445-2197.2010.05481.x. (PMID: 10.1111/j.1445-2197.2010.05481.x21418467)
      Nageswaran H, Haque A, Zia M, Hassn A (2017) Laparoscopic redo anti-reflux surgery: case-series of different presentations, varied management and their outcomes. Int J Surg 46:47–52. https://doi.org/10.1016/j.ijsu.2017.08.553. (PMID: 10.1016/j.ijsu.2017.08.55328821410)
      Ceccarelli G, Valeri M, Amato L et al (2023) Robotic revision surgery after failed Nissen anti-reflux surgery: a single center experience and a literature review. J Robot Surg. https://doi.org/10.1007/s11701-023-01546-6. (PMID: 10.1007/s11701-023-01546-6368623489979125)
      Dreifuss NH, Mangano A, Hassan C, Masrur MA (2021) Robotic revisional bariatric surgery: a high-volume center experience. OBES SURG 31(4):1656–1663. https://doi.org/10.1007/s11695-020-05174-z. (PMID: 10.1007/s11695-020-05174-z33392998)
      Jawhar N, Sample JW, Salame M et al (2024) The trajectory of revisional bariatric surgery: open to laparoscopic to robotic. J Clin Med 13(7):1878. https://doi.org/10.3390/jcm13071878. (PMID: 10.3390/jcm130718783861064311012271)
      Evans L, Cornejo J, Elli EF (2024) Evolution of bariatric robotic surgery: revolutionizing weight loss procedures. Curr Surg Rep 12(6):129–137. https://doi.org/10.1007/s40137-024-00398-9. (PMID: 10.1007/s40137-024-00398-9)
      Wong SW, Crowe P (2023) Visualisation ergonomics and robotic surgery. J Robot Surg 17(5):1873–1878. https://doi.org/10.1007/s11701-023-01618-7. (PMID: 10.1007/s11701-023-01618-73720464810492791)
      Cassilly R, Diodato MD, Bottros M, Damiano RJ (2004) Optimizing motion scaling and magnification in robotic surgery. Surgery 136(2):291–294. https://doi.org/10.1016/j.surg.2004.05.002. (PMID: 10.1016/j.surg.2004.05.00215300193)
      Van Beek DB, Auyang ED, Soper NJ (2011) A comprehensive review of laparoscopic redo fundoplication. Surg Endosc 25(3):706–712. https://doi.org/10.1007/s00464-010-1254-0. (PMID: 10.1007/s00464-010-1254-020661749)
      Del Campo SEM, Mansfield SA, Suzo AJ, Hazey JW, Perry KA (2017) Laparoscopic redo fundoplication improves disease-specific and global quality of life following failed laparoscopic or open fundoplication. Surg Endosc 31(11):4649–4655. https://doi.org/10.1007/s00464-017-5528-7. (PMID: 10.1007/s00464-017-5528-728389792)
      Schlottmann F, Laxague F, Angeramo CA, Sadava EE, Herbella FAM, Patti MG (2021) Outcomes of laparoscopic redo fundoplication in patients with failed antireflux surgery: a systematic review and meta-analysis. Ann Surg 274(1):78–85. https://doi.org/10.1097/SLA.0000000000004639. (PMID: 10.1097/SLA.000000000000463933214483)
      Lødrup A, Pottegård A, Hallas J, Bytzer P (2014) Use of proton pump inhibitors after antireflux surgery: a nationwide register-based follow-up study. Gut 63(10):1544–1549. https://doi.org/10.1136/gutjnl-2013-306532. (PMID: 10.1136/gutjnl-2013-30653224474384)
      Wijnhoven BPL, Lally CJ, Kelly JJ, Myers JC, Watson DI (2008) Use of antireflux medication after antireflux surgery. J Gastrointest Surg 12(3):510–517. https://doi.org/10.1007/s11605-007-0443-1. (PMID: 10.1007/s11605-007-0443-118071830)
    • Contributed Indexing:
      Keywords: Gastroesophageal reflux disease; Minimally invasive surgery; Nissen fundoplication; Revisional surgery; Toupet fundoplication
    • Publication Date:
      Date Created: 20241107 Date Completed: 20241107 Latest Revision: 20241224
    • Publication Date:
      20241224
    • Accession Number:
      10.1007/s11701-024-02124-0
    • Accession Number:
      39508953