The effect of compression therapies and therapeutic modalities on lymphedema secondary to cancer: a rapid review and evidence map.

Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE

Publication: 2011- : New York : Springer
Original Publication: Northwood, Middlesex, England : Science and Technology Letters, c1994-

Lymphedema*/therapy ; Lymphedema*/etiology ; Compression Bandages* ; Neoplasms*/complications ; Neoplasms*/therapy; Humans ; Female

The identification of effective therapeutic modalities to manage lymphedema secondary to cancer is a high priority among patients and clinicians. Complex decongestive therapy (CDT) remains a fundamental intervention for individuals with lymphedema; however, interventions involving modalities such as low level laser therapy, specially designed compression systems, and compression pumps may be helpful to improve outcomes and reduce costs of care. We conducted a rapid review of the literature examining compression therapies and therapeutic modalities in the treatment of lymphedema secondary to cancer. A search of the electronic databases from June 2018 to October 2023 was performed including MEDLINE, EMBASE, and CINAHL. The electronic search yielded 438 potentially relevant citations with 40 randomized controlled trials included in the review, and 30 in the mapping process. Ninety-three percent (n = 37) of the trials included participants with a diagnosis of breast cancer. Across all categories and domains, all but two trials were rated as having 'some concerns' or a 'high risk of bias'. Intervention effects ranged from clinically insignificant to large effects on lymphedema volume. Evidence mapping suggests potential for benefit from (1) compression garments for the prevention of lymphedema, (2) interventions added to CDT in the intensive reduction phase, and (3) nighttime compression and compression pump treatments in the maintenance phase. A multi-centre collaborative research approach is needed to support the conduct of high-quality large-scale trials to inform the optimal type, timing, and combination of compression therapies and therapeutic modalities in the treatment of lymphedema secondary to cancer.
(© 2024. The Author(s).)

Lymphat Res Biol. 2014 Jun;12(2):103-9. (PMID: 24927065)
Arch Phys Med Rehabil. 2016 Sep;97(9):1520-1525. (PMID: 26987620)
Ann Rehabil Med. 2019 Dec;43(6):677-685. (PMID: 31918530)
Cancer. 2022 Feb 01;128(3):587-596. (PMID: 34614195)
Eur J Breast Health. 2023 Jan 1;19(1):34-44. (PMID: 36605467)
BMC Cancer. 2022 Aug 30;22(1):937. (PMID: 36042421)
Integr Cancer Ther. 2019 Jan-Dec;18:1534735419847276. (PMID: 31068019)
Support Care Cancer. 2017 Aug;25(8):2455-2462. (PMID: 28281052)
Lymphat Res Biol. 2019 Feb;17(1):70-77. (PMID: 30339481)
Physiother Theory Pract. 2018 May;34(5):337-345. (PMID: 29308967)
BMJ Evid Based Med. 2019 Dec;24(6):209-211. (PMID: 30777860)
Lymphology. 2019;52(2):82-91. (PMID: 31525829)
Breast Cancer Res Treat. 2024 Jun;205(2):359-370. (PMID: 38424364)
EClinicalMedicine. 2023 Dec 22;67:102397. (PMID: 38152415)
Physiother Theory Pract. 2016 Aug;32(6):446-451. (PMID: 27260219)
Lymphology. 2019;52(4):166-176. (PMID: 32171183)
Lymphat Res Biol. 2019 Jun;17(3):356-361. (PMID: 30358472)
Int J Mol Sci. 2024 Mar 31;25(7):. (PMID: 38612716)
Int J Gynecol Cancer. 2020 Jun;30(6):757-763. (PMID: 32107315)
Syst Rev. 2023 Mar 15;12(1):45. (PMID: 36918977)
Cancer. 2021 Jan 15;127(2):291-299. (PMID: 33079411)
Arch Phys Med Rehabil. 2022 Feb;103(2):353-363. (PMID: 34407446)
J Clin Epidemiol. 2011 Apr;64(4):380-2. (PMID: 21185693)
J Cancer Surviv. 2019 Oct;13(5):804-814. (PMID: 31446591)
Lymphology. 2021;54(1):41-51. (PMID: 34506086)
J Clin Med. 2022 Nov 15;11(22):. (PMID: 36431224)
Sci Rep. 2022 Aug 17;12(1):14005. (PMID: 35977981)
Lymphat Res Biol. 2015 Jun;13(2):146-53. (PMID: 25748341)
Lymphology. 2010 Mar;43(1):25-33. (PMID: 20552817)
Prz Menopauzalny. 2014 Sep;13(4):221-6. (PMID: 26327858)
Biomed Res Int. 2013;2013:767106. (PMID: 24377096)
Front Rehabil Sci. 2021 Nov 26;2:727256. (PMID: 36188772)
Cancer Nurs. 2022 Jul-Aug 01;45(4):E736-E745. (PMID: 34483287)
J Clin Epidemiol. 2011 Dec;64(12):1283-93. (PMID: 21839614)
Physiother Theory Pract. 2023 Sep 2;39(9):1832-1846. (PMID: 35343369)
Syst Rev. 2015 Jan 14;4:4. (PMID: 25589399)
Acta Oncol. 2022 Jul;61(7):897-905. (PMID: 35657063)
Cost Eff Resour Alloc. 2023 Jul 29;21(1):47. (PMID: 37516870)
Cancer. 2003 Sep 15;98(6):1114-22. (PMID: 12973834)
Cancer Med. 2023 Mar;12(5):5506-5516. (PMID: 36507561)
J Clin Epidemiol. 2012 Jun;65(6):602-9. (PMID: 22424985)
JAMA. 2001 Apr 18;285(15):1992-5. (PMID: 11308436)
Photodermatol Photoimmunol Photomed. 2017 Jan;33(1):32-40. (PMID: 27943450)
Arch Dis Child Educ Pract Ed. 2018 Jun;103(3):163-166. (PMID: 28667046)
Nat Rev Dis Primers. 2019 Mar 28;5(1):22. (PMID: 30923312)
Eur J Oncol Nurs. 2014 Dec;18(6):585-90. (PMID: 25066648)
Lymphology. 2018;51(4):174-183. (PMID: 31119907)
BMJ. 2011 Oct 18;343:d5928. (PMID: 22008217)
Cancer. 2002 Dec 1;95(11):2260-7. (PMID: 12436430)
Clin Rehabil. 2019 Apr;33(4):631-641. (PMID: 30607986)
Curr Oncol. 2021 Jan 13;28(1):455-470. (PMID: 33450972)
Lymphat Res Biol. 2023 Feb;21(1):52-59. (PMID: 35675677)
Support Care Cancer. 2012 Dec;20(12):3279-86. (PMID: 22549506)
J Vasc Surg Venous Lymphat Disord. 2022 Nov;10(6):1359-1366.e1. (PMID: 35952956)
Clin Rehabil. 2020 Sep;34(9):1230-1241. (PMID: 32580577)
J Clin Oncol. 2022 Jun 20;40(18):2004-2012. (PMID: 35108031)
Photomed Laser Surg. 2009 Oct;27(5):763-9. (PMID: 19878027)
Support Care Cancer. 2019 May;27(5):1697-1708. (PMID: 30121786)
Lymphology. 2009 Dec;42(4):188-94. (PMID: 20218087)

Keywords: Cancer; Compression pumps; Compression therapies; Extracorporeal shockwave therapy; Low-level laser therapy; Lymphedema; Mapping review

Date Created: 20241017 Date Completed: 20241017 Latest Revision: 20241020

20241020

PMC11486789

10.1007/s12032-024-02447-w

39417951