Relationship between the effect of human chorionic gonadotropin treatment on the fifth day after artificial insemination and ovarian ultrasonographic findings and blood nutritional metabolic factors in dairy cows.

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  • Author(s): Kawahara N;Kawahara N; Endo N; Endo N; Tanaka T; Tanaka T
  • Source:
    Animal reproduction science [Anim Reprod Sci] 2024 Nov; Vol. 270, pp. 107616. Date of Electronic Publication: 2024 Oct 02.
  • Publication Type:
    Journal Article; Clinical Trial, Veterinary; Randomized Controlled Trial, Veterinary
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7807205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2232 (Electronic) Linking ISSN: 03784320 NLM ISO Abbreviation: Anim Reprod Sci Subsets: MEDLINE
    • Publication Information:
      Original Publication: Amsterdam, Elsevier Scientific Pub. Co.
    • Subject Terms:
      Chorionic Gonadotropin*/pharmacology ; Chorionic Gonadotropin*/administration & dosage ; Insemination, Artificial*/veterinary ; Ovary*/drug effects ; Ovary*/diagnostic imaging ; Ovary*/metabolism; Female ; Animals ; Cattle/physiology ; Pregnancy ; Ultrasonography/veterinary ; Insulin/blood ; Progesterone/blood ; Progesterone/pharmacology
    • Abstract:
      The objective of the present study was to determine the ovarian ultrasonographic findings and metabolic factors that influence the effect of human chorionic gonadotropin (hCG) treatment on the fifth day after artificial insemination (AI) in dairy cows. Thirty-seven lactating Holstein cows were assigned to two groups: the hCG group (n = 25), which received 3000 IU of hCG intramuscularly on Day 5 after AI (day of AI = Day 0), and the control group (n = 12), which received no treatment. Ovarian ultrasonography measured luteal tissue area (LTA), luteal blood flow area (LBF), relative LBF (= LBF/LTA), and dominant follicle area on Day 5. Blood tests measured plasma insulin-like growth factor-I, insulin, and metabolite concentrations on Day 5 and plasma progesterone concentrations on Days 5 and 7. LBF was greater in pregnant cows than in non-pregnant cows, and plasma Glu concentration was lesser in pregnant cows than in non-pregnant cows, but in both cases there was no interaction between group and pregnancy outcome. For plasma insulin concentration, there was an interaction between group and pregnancy outcome, with pregnant cows in the hCG group having lesser concentrations than the other groups. Logistic regression analysis showed that group and the interaction between group and plasma insulin concentration were associated with pregnancy outcome. These results suggest that the effect of hCG treatment on Day 5 after AI is related to plasma insulin concentration and is more effective in cows with lesser plasma insulin concentrations.
      Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2024 Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: Dairy cow; Human chorionic gonadotropin; Metabolic hormone; Ovarian ultrasonography; Pregnancy rate; Progesterone
    • Accession Number:
      0 (Chorionic Gonadotropin)
      0 (Insulin)
      4G7DS2Q64Y (Progesterone)
    • Publication Date:
      Date Created: 20241008 Date Completed: 20241031 Latest Revision: 20241120
    • Publication Date:
      20241121
    • Accession Number:
      10.1016/j.anireprosci.2024.107616
    • Accession Number:
      39378694